Abstract

BACKGROUND: Validation of the 99mTc-DMSA planar scintigraphy accuracy for split renal function assessment and comparison with evaluation based on SPECT imaging both with and without CT attenuation correction.
MATERIALS AND METHODS: For split renal function assessment two methods were used: A) planar scintigraphy based on anterior and posterior projections using correction for kidney depth calculated by the geometric mean; B) semi-quantitative evaluation based on SPECT (B1) and attenuation-corrected SPECT/CT (B2) images using locally developed software for kidney segmentation and voxel-based analysis. All three methods were performed with a phantom simulating body including pair of kidneys. For patient study methods A and B1 were applied on a group of 140 children and adolescents with various renal diseases. Renal function ratios were compared both mutually and with physically measured activity ratios in the phantom.
RESULTS: Method A provided results which were closest to measured reference values (average absolute difference of 0.9 percentage points [pp]). Method B1 was noticeably worse (2.1pp), whereas attenuation correction (B2) improved tomography results considerably (1.3 pp). The superiority of planar imaging could be caused among others by differences in creation of planar range of interest compared to tomographic volume of interest. However all the differences were under the threshold of any clinical importance. The comparison between method A and B1 based on patient study also showed differences mostly of none clinical importance.
CONCLUSION: Routine evaluation of split renal function using planar technique with correction of the kidney depth is at least equivalent to tomographic evaluation, and there is no need to update the established clinical practice.

Details

Title
Comparison of planar DMSA scan with an evaluation based on SPECT imaging in the split renal function assessment
Author
Chroustová, Daniela 1 ; Trnka, Jirí 2 ; Šírová, Veřa 2 ; Urbanova, Ivana 3 ; Langer, Jan 4 ; Kubinyi, Jozef 2 

 Department of Nuclear Medicine, General University Hospital and First Faculty of Medicine, Charles University in Prague,. [email protected] 
 Department of Nuclear Medicine, General University Hospital and First Faculty of Medicine, Charles University in Prague, 
 Department of Paediatrics, Hospital Na Bulovce, Prague 
 Clinic of Paediatrics and Adolescent Medicine, General University Hospital and First. Faculty of Medicine, Charles University in Prague, 
First page
12
End page
17
Publication year
2016
Publication date
2016
Publisher
Wydawnictwo Via Medica
ISSN
15069680
e-ISSN
16444345
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2464227345
Copyright
© 2016. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.