Abstract

Evidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

Details

Title
Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study
Author
Pantea Stoian Anca 1 ; Pricop-Jeckstadt Mihaela 2 ; Pana Adrian 3 ; Bogdan-Vasile, Ileanu 3 ; Schitea Ruxandra 4 ; Geanta Marius 4 ; Catrinoiu Doina 5 ; Suceveanu, Andra Iulia 5 ; Serafinceanu Cristian 1 ; Pituru Silviu 6 ; Poiana Catalina 6 ; Timar Bogdan 7 ; Nitipir Cornelia 6 ; Parvu Simona 6 ; Arsene Andreea 6 ; Mazilu, Laura 5 ; Toma Antonela 8 ; Hainarosie Razvan 9 ; Ceriello Antonio 10 ; Rizzo Manfredi 11 ; Jinga Viorel 6 

 University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania (GRID:grid.8194.4) (ISNI:0000 0000 9828 7548); Nutrition and Metabolic Diseases “N. C. Paulescu”, National Institute of Diabetes, Bucharest, Romania (GRID:grid.8194.4) 
 University POLITEHNICA of Bucharest, Department of Applied Mathematics, Bucharest, Romania (GRID:grid.4551.5) (ISNI:0000 0001 2109 901X); University Politehnica of Bucharest, Center for Research and Training in Innovative Techniques of Applied Mathematics in Engineering-Traian Lalescu-(CiTi), Bucharest, Romania (GRID:grid.4551.5) (ISNI:0000 0001 2109 901X) 
 Center for Health Outcomes & Evaluation, Bucharest, Romania (GRID:grid.4551.5) 
 Center for Innovation in Medicine, Bucharest, Romania (GRID:grid.4551.5) 
 Ovidius University of Constanta, Department of Internal Medicine, Faculty of Medicine, Constanţa, Romania (GRID:grid.412430.0) (ISNI:0000 0001 1089 1079) 
 University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania (GRID:grid.8194.4) (ISNI:0000 0000 9828 7548) 
 Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania (GRID:grid.22248.3e) (ISNI:0000 0001 0504 4027) 
 University Politehnica of Bucharest, Center for Research and Training in Innovative Techniques of Applied Mathematics in Engineering-Traian Lalescu-(CiTi), Bucharest, Romania (GRID:grid.4551.5) (ISNI:0000 0001 2109 901X); University POLITEHNICA of Bucharest, Department of Mathematical Methods and Models, Bucharest, Romania (GRID:grid.4551.5) (ISNI:0000 0001 2109 901X) 
 University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania (GRID:grid.8194.4) (ISNI:0000 0000 9828 7548); Prof. Dr. D. Hociota” Institute of Phonoaudiology and Functional ENT Surgery, Bucharest, Romania (GRID:grid.8194.4) 
10  IRCCS MultiMedica, Milan, Italy (GRID:grid.420421.1) (ISNI:0000 0004 1784 7240) 
11  University of South Carolina, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Columbia, USA (GRID:grid.254567.7) (ISNI:0000 0000 9075 106X); University of Palermo, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Palermo, Italy (GRID:grid.10776.37) (ISNI:0000 0004 1762 5517) 
Publication year
2020
Publication date
2020
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2473302285
Copyright
© The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.