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Abstract
The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
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1 University of California, Division of Infectious Diseases, Department of Medicine, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811)
2 Chan-Zuckerberg Biohub, San Francisco, USA (GRID:grid.499295.a); University of California San Francisco, Department of Microbiology and Immunology, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811); University of California San Francisco, Department of Medicine and Biochemistry & Biophysics, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811)
3 University of California, Division of Infectious Diseases, Department of Medicine, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811); Chan-Zuckerberg Biohub, San Francisco, USA (GRID:grid.499295.a)
4 University of California, Department of Pathology and Laboratory Medicine, Davis School of Medicine, Sacramento, USA (GRID:grid.27860.3b) (ISNI:0000 0004 1936 9684)
5 University of California San Francisco, Department of Laboratory Medicine, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811)
6 Chan-Zuckerberg Biohub, San Francisco, USA (GRID:grid.499295.a); University of California San Francisco, Department of Medicine and Biochemistry & Biophysics, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811)