Abstract

Gravity determines shape of body tissue and affects the functions of life, both in plants and animals. The cellular response to gravity is an active process of mechanotransduction. Although plants and animals share some common mechanisms of gravity sensing in spite of their distant phylogenetic origin, each species has its own mechanism to sense and respond to gravity. In this review, we discuss current understanding regarding the mechanisms of cellular gravity sensing in plants and animals. Understanding gravisensing also contributes to life on Earth, e.g., understanding osteoporosis and muscle atrophy. Furthermore, in the current age of Mars exploration, understanding cellular responses to gravity will form the foundation of living in space.

Details

Title
Gravity sensing in plant and animal cells
Author
Takahashi, Ken 1   VIAFID ORCID Logo  ; Takahashi, Hideyuki 2 ; Furuichi Takuya 3 ; Toyota Masatsugu 4   VIAFID ORCID Logo  ; Furutani-Seiki Makoto 5 ; Kobayashi Takeshi 6 ; Watanabe-Takano, Haruko 7 ; Shinohara Masahiro 8 ; Numaga-Tomita Takuro 9 ; Sakaue-Sawano Asako 10   VIAFID ORCID Logo  ; Miyawaki Atsushi 10 ; Naruse Keiji 1   VIAFID ORCID Logo 

1  Okayama University, Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan (GRID:grid.261356.5) (ISNI:0000 0001 1302 4472) 
2  Tohoku University, Graduate School of Life Sciences, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943) 
3  Hagoromo University of International Studies, Faculty of Human Life Sciences, Sakai, Japan (GRID:grid.448955.1) (ISNI:0000 0000 8889 9938) 
4  Saitama University, Department of Biochemistry and Molecular Biology, Saitama, Japan (GRID:grid.263023.6) (ISNI:0000 0001 0703 3735) 
5  Yamaguchi University, Department of Systems Biochemistry in Regeneration and Pathology, Graduate School of Medicine, Yamaguchi, Japan (GRID:grid.268397.1) (ISNI:0000 0001 0660 7960) 
6  Nagoya University, Department of Integrative Physiology, Graduate School of Medicine, Nagoya, Japan (GRID:grid.27476.30) (ISNI:0000 0001 0943 978X) 
7  National Cerebral and Cardiovascular Center Research Institute, Department of Cell Biology, Suita, Japan (GRID:grid.410796.d) (ISNI:0000 0004 0378 8307) 
8  National Rehabilitation Center for Persons with Disabilities, Department of Rehabilitation for the Movement Functions, Research Institute, Tokorozawa, Japan (GRID:grid.419714.e) (ISNI:0000 0004 0596 0617) 
9  Shinshu University School of Medicine, Department of Molecular Pharmacology, Matsumoto, Japan (GRID:grid.263518.b) (ISNI:0000 0001 1507 4692) 
10  Lab for Cell Function and Dynamics, CBS, RIKEN, Wakō, Japan (GRID:grid.474690.8) 
Publication year
2021
Publication date
2021
Publisher
Nature Publishing Group
e-ISSN
23738065
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41526-020-00130-8
ProQuest document ID
2487154304
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.