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Abstract
The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.
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1 Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia (GRID:grid.412460.5); Saint Petersburg State University, Institute of Chemistry, Saint Petersburg, Russia (GRID:grid.15447.33) (ISNI:0000 0001 2289 6897); A. M. Granov Russian Research Centre for Radiology and Surgical Technologies, Saint Petersburg, Russia (GRID:grid.15447.33)
2 Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia (GRID:grid.412460.5)
3 Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia (GRID:grid.412460.5); Saint Petersburg State University, Institute of Chemistry, Saint Petersburg, Russia (GRID:grid.15447.33) (ISNI:0000 0001 2289 6897)
4 Saint Petersburg State University, Institute of Chemistry, Saint Petersburg, Russia (GRID:grid.15447.33) (ISNI:0000 0001 2289 6897)
5 AQUANOVA RUS” JSC, Dubna, Russia (GRID:grid.15447.33)