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Copyright © 2021 Dong Peng et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/

Abstract

Purpose. The purpose of the current meta-analysis was to evaluate whether multidisciplinary team improved overall survival of colorectal cancer. Methods. PubMed, EMBASE, and Cochrane Library database were searched from inception to October 25, 2020. The hazard ratio (HR) and 95% confidence (CI) of overall survival (OS) were calculated. Results. A total of 11 studies with 30814 patients were included in this meta-analysis. After pooling the HRs, the MDT group was associated with better OS compared with the non-MDT group (HR=0.81, 95% CI 0.69-0.94, p=0.005). In subgroup analysis of stage IV colorectal cancer, the MDT group was associated with better OS as well (HR=0.73, 95% CI 0.59-0.90, p=0.004). However, in terms of postoperative mortality, no significant difference was found between MDT and non-MDT groups (OR=0.84, 95% CI 0.44-1.61, p=0.60). Conclusion. MDT could improve OS of colorectal cancer patients.

Details

Title
Improved Overall Survival of Colorectal Cancer under Multidisciplinary Team: A Meta-Analysis
Author
Peng, Dong  VIAFID ORCID Logo  ; Yu-Xi, Cheng; Cheng, Yong  VIAFID ORCID Logo 
Editor
Maciej Gagat
Publication year
2021
Publication date
2021
Publisher
John Wiley & Sons, Inc.
ISSN
23146133
e-ISSN
23146141
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2527983543
Copyright
Copyright © 2021 Dong Peng et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/