Patterns of Uveitis in Children According to Age: Comparison of Visual Outcomes and Complications in a Tertiary Center

Abstract

Background: Uveitis in the pediatric population is uncommon, accounting for 2 to 14% of all uveitis cases, yet resulting in significant ocular morbidity. A number of studies have focused on patterns and complications of uveitis in the pediatric age group (≤ 16 years). In this report, we studied children with uveitis syndromes focusing on demographics, anatomic distribution, etiologies, treatment, and complications. We additionally divided subjects into two age groups to look into any differential characteristics pertaining to the younger age group and the role of amblyopia as a cause of visual loss. Methods: Retrospective chart review of 80 eyes of 49 uveitis patients aged ≤16years. Subjects were categorized by age of onset into visually immature (≤8 years) and visually mature group (>8 years). Data compared between the two age groups included demographics, disease characteristics, visual outcomes and complications. Results: Idiopathic uveitis was the most common diagnosis (51%). Anterior uveitis complications (posterior synechiae and band keratopathy) were more common in the younger group (p=0.002 and p=0.03 respectively) while posterior uveitis manifestations (vitreous haze and vasculitis) were more common in the older age group (p=0.04 and p<0.001 respectively). Amblyopia was the most common cause of vision loss in the visually immature versus cataract in the visually mature. Conclusion: Anterior uveitis and its complications were more common in visually immature group in our cohort. Amblyopia was identified as the main cause of visual loss in the younger population.

Keywords: Amblyopia; Complications; Pediatric; Uveitis