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© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

The non-steroidal anti-inflammatory drugs (NSAIDs) are the most used drugs in knee osteoarthritis (OA) treatment. Despite their efficiency in pain and inflammation alleviation, NSAIDs accumulate in the environment as chemical pollutants and have numerous genetic, morphologic, and functional negative effects on plants and animals. Ultrasound (US) therapy can improve pain, inflammation, and function in knee OA, without impact on environment, and with supplementary metabolic beneficial effects on cartilage compared to NSAIDs. These features recommend US therapy as alternative for NSAIDs use in knee OA treatment.

Details

Title
Can Ultrasound Therapy Be an Environmental-Friendly Alternative to Non-Steroidal Anti-Inflammatory Drugs in Knee Osteoarthritis Treatment?
Author
Ungur, Rodica Ana 1   VIAFID ORCID Logo  ; Viorela, Mihaela Ciortea 1 ; Irsay, Laszlo 1 ; Ciubean, Alina Deniza 1 ; Năsui, Bogdana Adriana 2   VIAFID ORCID Logo  ; Răzvan, Andrei Codea 3 ; Singurean, Victoria Emilia 1 ; Groza, Oana Bianca 1 ; Căinap, Simona 4 ; Martiș, Georgiana Smaranda 5 ; Borda, Cristin 3 ; Borda, Ileana Monica 1 

 Department of Medical Specialties, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania; [email protected] (R.A.U.); [email protected] (L.I.); [email protected] (A.D.C.); [email protected] (V.E.S.); [email protected] (O.B.G.); [email protected] (I.M.B.) 
 Department of Community Health, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania; [email protected] 
 Faculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania; [email protected] (R.A.C.); [email protected] (C.B.) 
 Department of Mother and Child, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania; [email protected] 
 Food Engineering Department, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400509 Cluj-Napoca, Romania 
First page
2715
Publication year
2021
Publication date
2021
Publisher
MDPI AG
e-ISSN
19961944
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2539937580
Copyright
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.