Abstract

A major health concern of the 21st century is the rise of multi-drug resistant pathogenic microbial species. Recent technological advancements have led to considerable opportunities for low-dimensional materials (LDMs) as potential next-generation antimicrobials. LDMs have demonstrated antimicrobial behaviour towards a variety of pathogenic bacterial and fungal cells, due to their unique physicochemical properties. This review provides a critical assessment of current LDMs that have exhibited antimicrobial behaviour and their mechanism of action. Future design considerations and constraints in deploying LDMs for antimicrobial applications are discussed. It is envisioned that this review will guide future design parameters for LDM-based antimicrobial applications.

Antimicrobial resistance is a growing global problem and low dimensional materials have emerged as a potential solution. Here, the authors review the progress which has been made on low dimensional antimicrobials looking at the materials synthesis, modes of action and currently applications.

Details

Title
Antipathogenic properties and applications of low-dimensional materials
Author
Shaw, Z L 1 ; Kuriakose Sruthi 2   VIAFID ORCID Logo  ; Cheeseman, Samuel 3 ; Dickey, Michael D 4   VIAFID ORCID Logo  ; Genzer, Jan 4 ; Christofferson, Andrew J 3   VIAFID ORCID Logo  ; Crawford, Russell J 3   VIAFID ORCID Logo  ; McConville, Chris F 5 ; Chapman, James 3   VIAFID ORCID Logo  ; Truong, Vi Khanh 6   VIAFID ORCID Logo  ; Elbourne, Aaron 3   VIAFID ORCID Logo  ; Walia Sumeet 2   VIAFID ORCID Logo 

 RMIT University, School of Engineering, Melbourne, Australia (GRID:grid.1017.7) (ISNI:0000 0001 2163 3550) 
 RMIT University, School of Engineering, Melbourne, Australia (GRID:grid.1017.7) (ISNI:0000 0001 2163 3550); RMIT University, Functional Materials and Microsystems Research Group, MicroNano Research Facility, Melbourne, Australia (GRID:grid.1017.7) (ISNI:0000 0001 2163 3550) 
 RMIT University, School of Science, Melbourne, Australia (GRID:grid.1017.7) (ISNI:0000 0001 2163 3550) 
 North Carolina State University, Department of Chemical and Biomolecular Engineering, Raleigh, USA (GRID:grid.40803.3f) (ISNI:0000 0001 2173 6074) 
 Deakin University, Geelong, Institute for Frontier Materials, Victoria, Australia (GRID:grid.1021.2) (ISNI:0000 0001 0526 7079) 
 RMIT University, School of Science, Melbourne, Australia (GRID:grid.1017.7) (ISNI:0000 0001 2163 3550); North Carolina State University, Department of Chemical and Biomolecular Engineering, Raleigh, USA (GRID:grid.40803.3f) (ISNI:0000 0001 2173 6074) 
Publication year
2021
Publication date
2021
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2544321464
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.