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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body. Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells to form the adipose tissue. Adipose-derived stem cells’ differentiation serves well beyond the simple goal of producing new adipocytes. Indeed, with the current immense biotechnological advances, the most critical role of adipose-derived stem cells remains their tremendous potential in the field of regenerative medicine. This review focuses on examining the physiological importance of adipogenesis, the current approaches that are employed to model this tightly controlled phenomenon, and the crucial role of adipogenesis in elucidating the pathophysiology and potential treatment modalities of human diseases. The future of adipogenesis is centered around its crucial role in regenerative and personalized medicine.

Details

Title
Modeling Adipogenesis: Current and Future Perspective
Author
Bahmad, Hisham F 1   VIAFID ORCID Logo  ; Daouk, Reem 1 ; Azar, Joseph 1 ; Sapudom, Jiranuwat 2   VIAFID ORCID Logo  ; Teo, Jeremy C M 2   VIAFID ORCID Logo  ; Abou-Kheir, Wassim 1   VIAFID ORCID Logo  ; Al-Sayegh, Mohamed 3   VIAFID ORCID Logo 

 Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, 1107 2260 Beirut, Lebanon; [email protected] (H.F.B.); [email protected] (R.D.); [email protected] (J.A.) 
 Laboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, 2460 Abu Dhabi, UAE; [email protected] 
 Biology Division, New York University Abu Dhabi, 2460 Abu Dhabi, UAE 
First page
2326
Publication year
2020
Publication date
2020
Publisher
MDPI AG
e-ISSN
20734409
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2548336474
Copyright
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.