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Abstract
Is engaging with music good for your mental health? This question has long been the topic of empirical clinical and nonclinical investigations, with studies indicating positive associations between music engagement and quality of life, reduced depression or anxiety symptoms, and less frequent substance use. However, many earlier investigations were limited by small populations and methodological limitations, and it has also been suggested that aspects of music engagement may even be associated with worse mental health outcomes. The purpose of this scoping review is first to summarize the existing state of music engagement and mental health studies, identifying their strengths and weaknesses. We focus on broad domains of mental health diagnoses including internalizing psychopathology (e.g., depression and anxiety symptoms and diagnoses), externalizing psychopathology (e.g., substance use), and thought disorders (e.g., schizophrenia). Second, we propose a theoretical model to inform future work that describes the importance of simultaneously considering music-mental health associations at the levels of (1) correlated genetic and/or environmental influences vs. (bi)directional associations, (2) interactions with genetic risk factors, (3) treatment efficacy, and (4) mediation through brain structure and function. Finally, we describe how recent advances in large-scale data collection, including genetic, neuroimaging, and electronic health record studies, allow for a more rigorous examination of these associations that can also elucidate their neurobiological substrates.
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Details
; Coleman, Peyton L 2
; Iversen, John R 3 ; Maes, Hermine H 4 ; Gordon, Reyna L 5 ; Lense, Miriam D 6 1 Vanderbilt University Medical Center, Department of Medicine, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916); Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916)
2 Vanderbilt University Medical Center, Department of Otolaryngology – Head & Neck Surgery, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916)
3 Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California, San Diego, La Jolla, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242)
4 Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Department of Human and Molecular Genetics, Richmond, USA (GRID:grid.224260.0) (ISNI:0000 0004 0458 8737); Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Department of Psychiatry, Richmond, USA (GRID:grid.224260.0) (ISNI:0000 0004 0458 8737); Massey Cancer Center, Virginia Commonwealth University, Richmond, USA (GRID:grid.224260.0) (ISNI:0000 0004 0458 8737)
5 Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916); Vanderbilt University Medical Center, Department of Otolaryngology – Head & Neck Surgery, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916); Vanderbilt Brain Institute, Vanderbilt University, Nashville, USA (GRID:grid.152326.1) (ISNI:0000 0001 2264 7217); The Curb Center, Vanderbilt University, Nashville, USA (GRID:grid.152326.1) (ISNI:0000 0001 2264 7217)
6 Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916); Vanderbilt Brain Institute, Vanderbilt University, Nashville, USA (GRID:grid.152326.1) (ISNI:0000 0001 2264 7217); The Curb Center, Vanderbilt University, Nashville, USA (GRID:grid.152326.1) (ISNI:0000 0001 2264 7217)




