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Abstract
We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites.
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Details
1 Universiti Teknologi MARA, Faculty of Medicine, Sungai Buloh, Malaysia (GRID:grid.412259.9) (ISNI:0000 0001 2161 1343); Universiti Teknologi MARA, Faculty of Dentistry, Sungai Buloh, Malaysia (GRID:grid.412259.9) (ISNI:0000 0001 2161 1343)
2 Universiti Teknologi MARA, Faculty of Medicine, Sungai Buloh, Malaysia (GRID:grid.412259.9) (ISNI:0000 0001 2161 1343)
3 Universiti Putra Malaysia, Faculty of Science, Serdang, Malaysia (GRID:grid.11142.37) (ISNI:0000 0001 2231 800X)