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© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

We are reporting a case of a 36 year-old Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) positive hypertensive primigravida with postpartum uterine atony that required emergency subtotal hysterectomy at Saint John Hospital Bucur Maternity Bucharest. The maternity was designated as the Coronavirus Disease 2019 (COVID-19) Maternity for Bucharest and Ilfov County since March 2020. The patient was mildly symptomatic for SARS-CoV-2, infection confirmed with reverse transcription polymerase chain reaction (RT-PCR). The caesarean section was performed and a live male fetus was born, 2630 g and Apgar Score of 9 (the male fetus was negative for SARS-CoV-2). Postpartum hysterectomy with adnexal preservation was performed because of uterine atony. The postoperative evolution was favorable. The patient was discharged with her baby 10 days after birth. Given the limited resources, the placenta, the umbilical cord and the uterus were not tested for SARS-CoV-2. The pathology exam revealed that on the maternal side there were specific uterine atony lesions as well as endometrial and miometrial ischaemia. The placenta had nonspecific findings: chronic ischemic lesions with small villi, fibrin deposits in the materno-fetal interface. The peculiarity of the case is that we report the morphological findings of the placenta and uterus resulted from intrapartum uterine atonia in a patient with gestational arterial hypertension, premature birth and COVID-19. Further studies are required to characterize the pattern of such intricate conditions.

Details

Title
Can SARS-CoV-2 Induce Uterine Vascular Anomalies and Poor Contractile Response?—A Case Report
Author
Lesnic, Anca 1 ; Bashar Haj Hamoud 2 ; Mircea-Octavian Poenaru 3 ; Moldovan, Valentin-Tiberiu 4 ; Chicea, Radu 5 ; Romina-Marina Sima 3   VIAFID ORCID Logo  ; Popescu, Mihai 6   VIAFID ORCID Logo  ; Ples, Liana 3 

 Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania; [email protected] (A.L.); [email protected] (M.-O.P.); [email protected] (R.-M.S.); [email protected] (L.P.); “Bucur” Maternity, Saint John Hospital, 012361 Bucharest, Romania; Department of PhD Studies, IOSUD, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania 
 Department for Gynaecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, Kirrberger Straße 100, Building 9, 66421 Homburg, Germany; [email protected] 
 Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania; [email protected] (A.L.); [email protected] (M.-O.P.); [email protected] (R.-M.S.); [email protected] (L.P.); “Bucur” Maternity, Saint John Hospital, 012361 Bucharest, Romania 
 Department of Pathology “Victor Babeş”, National Institute for Research and Development in Pathology and Biomedical Sciences, 050096 Bucharest, Romania; [email protected] 
 Medicine Faculty, Lucian Blaga University, 550024 Sibiu, Romania; [email protected] 
 Department of Anaesthesia and Critical Care, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania 
First page
670
Publication year
2021
Publication date
2021
Publisher
MDPI AG
ISSN
1010660X
e-ISSN
16489144
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2554605979
Copyright
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.