Abstract

Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden’s Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.

Details

Title
Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
Author
Chia-Chi, Yen 1 ; Wei-Chun, Lin 2 ; Wang, Tzu-Hao 2 ; Guan-Fan, Chen 2 ; Da-Ying, Chou 2 ; Dian-Min, Lin 2 ; Shu-Yuan, Lin 2 ; Min-Ho, Chan 3 ; Jia-Ming, Wu 4 ; Chin-Dar, Tseng 5 ; Yu-Jie, Huang 6 ; Lee, Tsair-Fwu 7 

 Kaohsiung Municipal Min-Sheng Hospital, Department of Orthopedic, Kaohsiung, Taiwan; Hung-Kuang University, Department of Nutrition, Institute of Biomedical Nutrition, Taichung, Taiwan (GRID:grid.411432.1) (ISNI:0000 0004 1770 3722); National Sun Yat-Sen University, Department of Business Management, Kaohsiung, Taiwan (GRID:grid.412036.2) (ISNI:0000 0004 0531 9758) 
 Kaohsiung Municipal Min-Sheng Hospital, Department of Orthopedic, Kaohsiung, Taiwan (GRID:grid.412036.2) 
 Kaohsiung Municipal Min-Sheng Hospital, Department of Orthopedic, Kaohsiung, Taiwan (GRID:grid.412036.2); National Sun Yat-Sen University, Department of Business Management, Kaohsiung, Taiwan (GRID:grid.412036.2) (ISNI:0000 0004 0531 9758) 
 Chengde Medical University, Department of Biomedicine Engineering, Chengde, China (GRID:grid.413851.a) (ISNI:0000 0000 8977 8425) 
 National Kaohsiung University of Science and Technology, Medical Physics and Informatics Laboratory of Electronics Engineering, Kaohsiung, Taiwan, ROC (GRID:grid.412071.1) (ISNI:0000 0004 0639 0070) 
 Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Department of Radiation Oncology, Kaohsiung, Taiwan, ROC (GRID:grid.145695.a) 
 National Kaohsiung University of Science and Technology, Medical Physics and Informatics Laboratory of Electronics Engineering, Kaohsiung, Taiwan, ROC (GRID:grid.412071.1) (ISNI:0000 0004 0639 0070); Ph.D. Program in Biomedical Engineering, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC (GRID:grid.412019.f) (ISNI:0000 0000 9476 5696) 
Publication year
2021
Publication date
2021
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2557676502
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.