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© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Hypertension during pregnancy causes a greater risk of adverse birth outcomes worldwide; however, formal evidence of hypertensive disorders during pregnancy (HDP) in Japan is limited. We aimed to understand the association between maternal characteristics, HDP, and birth outcomes. In total, 18,833 mother-infant pairs were enrolled in the Hokkaido study on environment and children’s health, Japan, from 2002 to 2013. Medical records were used to identify hypertensive disorders and birth outcomes, namely, small for gestational age (SGA), SGA at full term (term-SGA), preterm birth (PTB), and low birth weight (LBW). The prevalence of HDP was 1.9%. Similarly, the prevalence of SGA, term-SGA, PTB, and LBW were 7.1%, 6.3%, 7.4%, and 10.3%, respectively. The mothers with HDP had increased odds of giving birth to babies with SGA (2.13; 95% Confidence Interval (CI): 1.57, 2.88), PTB (3.48; 95%CI: 2.68, 4.50), LBW (3.57; 95%CI: 2.83, 4.51) than normotensive pregnancy. Elderly pregnancy, low and high body mass index, active and passive smoking exposure, and alcohol consumption were risk factors for different birth outcomes. Therefore, it is crucial for women of reproductive age and their families to be made aware of these risk factors through physician visits, health education, and various community-based health interventions.

Details

Title
Hypertensive Disorders during Pregnancy (HDP), Maternal Characteristics, and Birth Outcomes among Japanese Women: A Hokkaido Study
Author
Poudel, Kritika 1 ; Kobayashi, Sumitaka 2 ; Miyashita, Chihiro 2 ; Ikeda-Araki, Atsuko 2   VIAFID ORCID Logo  ; Tamura, Naomi 2   VIAFID ORCID Logo  ; Yu Ait Bamai 2 ; Itoh, Sachiko 2 ; Yamazaki, Keiko 2 ; Masuda, Hideyuki 2 ; Itoh, Mariko 2 ; Ito, Kumiko 3 ; Kishi, Reiko 2 

 Faculty of Health Sciences, Hokkaido University, Sapporo 060-0812, Japan; [email protected] 
 Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan; [email protected] (S.K.); [email protected] (C.M.); [email protected] (A.I.-A.); [email protected] (N.T.); [email protected] (Y.A.B.); [email protected] (S.I.); [email protected] (K.Y.); [email protected] (H.M.); [email protected] (M.I.); [email protected] (K.I.) 
 Center for Environmental and Health Sciences, Hokkaido University, Sapporo 060-0812, Japan; [email protected] (S.K.); [email protected] (C.M.); [email protected] (A.I.-A.); [email protected] (N.T.); [email protected] (Y.A.B.); [email protected] (S.I.); [email protected] (K.Y.); [email protected] (H.M.); [email protected] (M.I.); [email protected] (K.I.); Faculty of Health Sciences, Hokkaido University of Science, Sapporo 060-0812, Japan 
First page
3342
Publication year
2021
Publication date
2021
Publisher
MDPI AG
ISSN
1661-7827
e-ISSN
1660-4601
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2566031533
Copyright
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.