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Abstract
Similar to global trends, the incidence rate of tuberculosis (TB) in China declined from 2000 to 2018. In this study, we aimed to evaluate TB trends in northern Guizhou Province and identify risk factors associated with rifampicin-resistant (RR) and concurrent extrapulmonary TB (EPTB). We analyzed data of TB patients hospitalized in Affiliated Hospital of Zunyi Medical University from 2011 to 2018, and assessed correlations between demographic characteristics of patients and RR-TB as well as concurrent EPTB. Our results showed that numbers of new, retreated, RR-TB and concurrent EPTB cases increased gradually from 2011 to 2018. Retreated patients had the highest odds of RR-TB but a lower likelihood of concurrent EPTB compared to new patients. Patients between 21 and 40 years of age had a higher likelihood of RR-TB compared to those 20 years and younger. Female patients and patients from Bijie city as well as the Miao ethnic minority had higher odds of concurrent EPTB. In summary, our data demonstrate upward trends in new, rifampicin-resistant and concurrent extrapulmonary TB cases in northern Guizhou Province of China, which should not be overlooked especially during and post the COVID-19 pandemic because TB is a greater long-term global health threat than COVID-19.
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Details
1 Affiliated Hospital of Zunyi Medical University, Tuberculosis Division of Respiratory and Critical Care Medicine, Zunyi, China (GRID:grid.413390.c)
2 Zunyi Medical University, Institute of Life Sciences, Zunyi, China (GRID:grid.417409.f) (ISNI:0000 0001 0240 6969)
3 Affiliated Hospital of Zunyi Medical University, Tuberculosis Division of Respiratory and Critical Care Medicine, Zunyi, China (GRID:grid.413390.c); Z-BioMed, Inc., Rockville, USA (GRID:grid.413390.c)