Abstract

Gut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, many studies have shown that probiotic supplementation can effectively improve sports performance. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of 2008 Olympic women's 48 kg weightlifting gold medalist and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0, 2.05 × 109, 4.10 × 109 and 1.03 × 1010 CFU/kg/day groups and were fed by oral gavage once daily for 4 weeks. The results showed that 4 weeks of PL-02 supplementation could significantly increase muscle mass, muscle strength and endurance performance, and hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise (p < 0.05). We believe that PL-02 can be used as a supplement to improve exercise performance and for its anti-fatigue effect.

Details

Title
Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
Author
Mon-Chien, Lee 1 ; Yi-Ju, Hsu 1 ; Ho Hsieh‐Hsun 2 ; Kuo Yi‐Wei 2 ; Wen-Yang, Lin 2 ; Shin-Yu, Tsai 2 ; Wei-Ling, Chen 3 ; Che-Li, Lin 4 ; Chi-Chang, Huang 1 

 National Taiwan Sport University, Graduate Institute of Sports Science, Taoyuan City, Taiwan (GRID:grid.412092.c) (ISNI:0000 0004 1797 2367) 
 Bioflag Biotech Co, Ltd, Research and Development Department, Tainan, Taiwan (GRID:grid.412092.c) 
 National Taiwan Sport University, Department of Sports Training Science-Athletics, Taoyuan City, Taiwan (GRID:grid.412092.c) (ISNI:0000 0004 1797 2367) 
 Taipei Medical University, Department of Orthopedics, School of Medicine, College of Medicine, Taipei City, Taiwan (GRID:grid.412896.0) (ISNI:0000 0000 9337 0481) 
Publication year
2021
Publication date
2021
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2577915148
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.