Relationship of Genetic Polymorphism For CYP19 Gen of Exon 3 With Quantity and Milk Composition in Domestic Female Goats

Abstract

This study was carried out to investigate the effect of the genetic polymorphism of the third exon for CYP19 gene on the quantity and composition of milk in local female goats. Blood samples were collected from female goats in the fields of some breeder in Babil Governorate/Al-Qasim City. Milk composition were examined in the Public Health Laboratory at Al-Qasim Green University/College of Veterinary Medicine, the genetic bundle of the third axon of the CYP19 gene was isolated, which was 140 bp in size, and its genotyping was determined according to the different nucleotide sequences and their association with the quantity and milk composition in the samples which tested in the Bayolat Laboratory in Al-Diwaniyah Governorate. The proportions of the distribution of the genotypes of the CYP19 gene in a sample of local female goats TT, GG and TG were 33.34%, 26.66 and 40%, respectively. The results showed prevalence of the TG genotype for CYP19 gene in the Iraqi local goats on the pure genotypes TT and GG, which was a highly significant superior (P<0.01) in the percentages of fat, protein, lactose and CFPP, as well as the significant superiority of the mixed genotype significantly on the pure genotype in the percentages of solid non-fat and density. It could be concluded from the current study that the selection of females with TG genotype as source for future generations to obtain a generation selected for the desired traits.