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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Background: Vertebral compression fractures, resulting in significant pain and disability, commonly occur in elderly osteoporotic patients. However, the current literature lacks long-term follow-up information related to image parameters and bone formation following vertebroplasty. Purpose: To evaluate new bone formation after vertebroplasty and the long-term effect of vertebroplasty. Methods: A total of 157 patients with new osteoporotic compression fractures who underwent vertebroplasty were retrospectively analyzed. The image parameters, including wedge angles, compression ratios, global alignment, and new bone formation, were recorded before and after vertebroplasty up to three years postoperatively. Results: The wedge angle improved and was maintained for 12 months. The compression ratios also improved but gradually deteriorated during the follow-up period. New bone formation was found in 40% of the patients at 36 months, and the multivariate analysis showed that this might have been related to the correction of the anterior compression ratio. Conclusions: Vertebroplasty significantly restored the wedge angles and compression ratios up to one year postoperatively, and new bone formation was noted on plain radiographs, which increased over time. Last, the restoration of vertebral parameters may contribute to new bone formation.

Details

Title
Healing of Vertebral Compression Fractures in the Elderly after Percutaneous Vertebroplasty—An Analysis of New Bone Formation and Sagittal Alignment in a 3-Year Follow-Up
Author
Kuo, Yuh-Ruey 1   VIAFID ORCID Logo  ; Ting-An, Cheng 1   VIAFID ORCID Logo  ; Chou, Po-Hsin 2 ; Yuan-Fu, Liu 3 ; Chao-Jui Chang 1 ; Cheng-Feng, Chuang 4 ; Pei-Fang, Su 4 ; Ruey-Mo, Lin 5 ; Cheng-Li, Lin 6 

 Department of Orthopedic Surgery, National Cheng Kung University Hospital, Tainan City 704, Taiwan; [email protected] (Y.-R.K.); [email protected] (T.-A.C.); [email protected] (C.-J.C.) 
 School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan; [email protected]; Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei 112, Taiwan 
 Department of Orthopedic Surgery, National Cheng Kung University Hospital Douliu Branch, Douliu City 640, Taiwan; [email protected] 
 Department of Statistics, National Cheng Kung University, Tainan City 701, Taiwan; [email protected] (C.-F.C.); [email protected] (P.-F.S.) 
 Department of Orthopedic Surgery, An-Nan Hospital, China Medical University, Tainan City 709, Taiwan; [email protected] 
 Department of Orthopedic Surgery, National Cheng Kung University Hospital, Tainan City 704, Taiwan; [email protected] (Y.-R.K.); [email protected] (T.-A.C.); [email protected] (C.-J.C.); Department of Orthopedics, College of Medicine, National Cheng Kung University, Tainan City 701, Taiwan; Musculoskeletal Research Center, Innovation Headquarter, National Cheng Kung University, Tainan City 701, Taiwan; Medical Device Innovation Center (MDIC), National Cheng Kung University, Tainan City 701, Taiwan 
First page
708
Publication year
2022
Publication date
2022
Publisher
MDPI AG
e-ISSN
20770383
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2627559814
Copyright
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.