It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
Environmental studies in several countries are including genotoxicity tests as tools to evaluate exposure to contaminants. Most of these tests are developed on sentinel species of mammals. The Ctenomys genus has been used as a sentinel for screening environmental contamination in several countries as Brazil, Chile, Argentina and Uruguay. One of the most used assays has been the in vivo micronucleus test which can be conducted easily on peripheral blood samples since the maturation of erythrocytes involves the loss of the major nucleus. The test potentially can detect genotoxic damage caused by chronic exposures. However, the results obtained may reflect chronic exposure depending on the spleen features that the species have. Until now, there are no studies to determine the role of the spleen in the Ctenomys genus. This note provides new data dealing with this subject and provides an anatomical interpretation of the results obtained. To determine chronic or recently exposure when a sentinel is used, is highly recommended to develop this kind of approaches.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer