Abstract

The objective was to evaluate the accuracy of B-mode ultrasonography and ARFI elastography in detecting malignancy in canine splenic lesions. Thirty-seven spleens with abnormalities (16 benign and 21 malignant) from dogs of different breeds and ages were evaluated. Echogenicity, echotexture, organ length and height were evaluated using B-mode. By ARFI elastography, tissue stiffness was evaluated qualitatively (elastogram) and quantitatively (measuring the shear wave velocity—SWV). Lesions were classified as diffuse, focal or multifocal (cranial, medial or caudal portion) and comparisons of the SWV between the injured and non-injured areas were performed. In the B-mode, no features were associated to malignancy (P > 0.05). In the elastogram, 35 spleens were non-deformable and 2 deformable, having no association with malignancy. The greater SWV was observed in malignant lesions (3.4 ± 0.6 m/s), followed by areas free from alterations (2.1 ± 0.3 m/s) and benign lesions (1.7 ± 0.5 m/s), with difference between groups (P < 0.0001). It was found that a SWV > 2.6 m/s indicates malignancy of canine splenic lesions (sensitivity of 95%, specificity of 100%, PPV of 100%, NPV of 94% and accuracy of 97%), concluding that ARFI elastography is a promising technique for differentiating malignancy in these lesions.

Details

Title
Accuracy of B-mode ultrasound and ARFI elastography in predicting malignancy of canine splenic lesions
Author
Maronezi, Marjury Cristina 1 ; Carneiro Rafael Kretzer 1 ; da Cruz Igor Cezar Kniphoff 1 ; de Oliveira Ana Paula Luiz 1 ; De Nardi Andrigo Barboza 1 ; Pavan Letícia 1 ; Del’Aguila-Silva Priscila 1 ; Uscategui Ricardo Andrés Ramirez 2 ; Feliciano Marcus Antônio Rossi 3 

 Paulista State University “Júlio de Mesquita Filho”, Faculty of Agrarian and Veterinary Sciences, Jaboticabal, Brazil (GRID:grid.410543.7) (ISNI:0000 0001 2188 478X) 
 Universidad CES, Medellin, Colombia (GRID:grid.411140.1) (ISNI:0000 0001 0812 5789) 
 Paulista State University “Júlio de Mesquita Filho”, Faculty of Agrarian and Veterinary Sciences, Jaboticabal, Brazil (GRID:grid.410543.7) (ISNI:0000 0001 2188 478X); Federal University of Santa Maria, Santa Maria, Brazil (GRID:grid.411239.c) (ISNI:0000 0001 2284 6531) 
Publication year
2022
Publication date
2022
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2638176880
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.