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Abstract
Exosomes derived from microRNA-138-5poverexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2 [RAW_REF_TEXT] Yiming Deng1,2,3 na1, [/RAW_REF_TEXT] [RAW_REF_TEXT] Duanduan Chen4 na1, [/RAW_REF_TEXT] [RAW_REF_TEXT] Feng Gao1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Hong Lv5, [/RAW_REF_TEXT] [RAW_REF_TEXT] Guojun Zhang5, [/RAW_REF_TEXT] [RAW_REF_TEXT] Xuan Sun1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Lian Liu1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Dapeng Mo1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Ning Ma1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Ligang Song1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Xiaochuan Huo1,2,3, [/RAW_REF_TEXT] [RAW_REF_TEXT] Tianyi Yan4, [/RAW_REF_TEXT] [RAW_REF_TEXT] Jingbo Zhang 1,2,3 & [/RAW_REF_TEXT] [RAW_REF_TEXT] Zhongrong Miao 1,2,3 [/RAW_REF_TEXT] Journal of Biological Engineering volume 16, Article number: 8 (2022) Cite this article [RAW_REF_TEXT] 134 Accesses [/RAW_REF_TEXT] [RAW_REF_TEXT] Metrics details [/RAW_REF_TEXT] The Original Article was published on 28 August 2019 Correction to: J Biol Eng 13, 71 (2019) https://doi.org/10.1186/s13036-019-0193-0 Figure 8 of the original article [1] unfortunately contained an error: Fig. 8 figure 1 BMSCs-derived exosomal miR-138-5p reduces neuron injury following IS in vivo. a, HE staining for hippocampal tissues of MCAO mouse models (scale bar = 25 μm); b, TUNEL staining to detect neuron apoptosis (scale bar = 25 μm) and quantitative analysis for the apoptotic rate; c, TTC staining showing the volume changes of cerebral infarction in mice and the corresponding quantitative analysis; d, Nissl staining (scale bar = 50 μm) showing the number of neurons and the corresponding quantitative analysis; e, quantitative analysis for LDH content; f, protein expression of inflammatory factors, proliferation and apoptosis marker proteins determined by Western blot analysis. LDH, lactate dehydrogenase; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; MCAO, middle cerebral artery occlusion; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; Bax, Bcl-2-associated X protein; Bcl-2, B-cell CLL/Lymphoma 2; IL-6, interleukin-6; IL-1β, interleukin-1β; TNF-α, tumor necrosis factor-α; BMSCs-control, MCAO mice without any treatment; BMSCs-miR-NC, MCAO mice injected with BMSCs-miR-NC exosomes; BMSCs-miR-138-5p, MCAO mice injected with BMSCs-miR-138-5p exosomes Full size image Correction Open Access Published:31 March 2022 [/RAW_REF_TEXT] Correction to:
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