Abstract
Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications. [...]we established this consensus statement on the diagnosis and management of ITP during pregnancy (detailed information is available in the Supplementary File, http://links.lww.com/CM9/A978). The recommended examinations for all patients include the following: a detailed patient and family history; a physical examination; complete blood count panels; reticulocyte and reticulated platelet counts; a peripheral blood smear; coagulation screening; human immunodeficiency virus, hepatitis B virus, and hepatitis C virus testing; liver and renal function tests; thyroid function tests; anti-nuclear antibody; and anti-phospholipid antibody tests. 3. Assessment of postpartum hemorrhage (PPH) We recommend evaluating PPH risk for ITP patients routinely to prevent life-threatening events associated with ITP by using the MONITOR model (maternal complication, World Health Organization bleeding score, antepartum platelet transfusion, placental abnormalities, platelet count, previous uterine surgery, and primiparity). Funding This work was supported by grants from the National Key Research and Development Program of China (No. 2017YFA0105503), the National Natural Science Foundation of China (No. 81970113), the Key Program of National Natural Science Foundation of China (No. 81730004), and the Beijing Natural Science Foundation (No.
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1 Department of Hematology, Peking University People's Hospital, Peking University Institute of Hematology, Beijing 100044, China
2 Department of Hematology, Xiangya Third Hospital, Central South University, Changsha, Hunan 410013, China
3 Department of Hematology, Xi Jing Hospital Affiliated to the Fourth Military Medical University, Xi’an, Shaanxi 710032, China
4 Department of Hematology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai 528404, China
5 Department of Hematology, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, China
6 Department of Hematology and Rheumatology, Qinghai Provincial People's Hospital, Xining, Qinghai 810007, China
7 Department of Internal Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China
8 Department of Hematology, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China
9 Department of Hematology, The Second Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an, Shaanxi 710004, China
10 Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250063, China
11 Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China
12 Department of Hematology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China
13 Department of Hematology, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing 100039, China
14 Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
15 Department of Hematology, Medical Center of Hematology, Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China
16 Department of Hematology, Tongji Hospital of Tongji University, Shanghai 200092, China
17 Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China
18 Department of Hematology, Qingdao Hiser Hospital Affiliated to Qingdao University, Qingdao, Shandong 266033, China
19 Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China
20 Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China
21 Department of Hematology, Affiliated Shanxi Big Hospital of Shanxi Medical University, Taiyuan, Shanxi 030032, China
22 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada
23 Department of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China
24 Department of Hematology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China
25 Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050004, China
26 Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University/Henan Cancer Hospital, Zhengzhou, Henan 450003, China
27 Department of Hematology, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China
28 Department of Hematology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, China
29 Department of International Medical Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
30 Department of Hematology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Disease, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
31 Department of Hematology, The First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang 832000, China
32 Department of Hematology, XiangYa Hospital, Central South University, Changsha, Hunan 410008, China
33 Department of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
34 Department of Hematology, First People's Hospital of Yunnan Province, Kunming, Yunnan 650034, China
35 Department of Hematology, The Second Affiliate Hospital of Nanchang University, Nanchang, Jiangxi 330006, China
36 Department of Hematology, Institute of Molecular Hematology, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan 410011, China
37 Department of Hematology, Lanzhou University Second Hospital, Lanzhou, Gansu 730030, China
38 Department of Hematology, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
39 Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
40 Department of Hematology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650106, China