Chemical Profile of Malva Neglecta and Malvella Sherardiana By Lc-Ms/Ms, Gc/Ms And Their Anticholinesterase, Antimicrobial and Antioxidant Properties with Aflatoxin-Contents

Abstract

The purpose of the present work was to calculate the phenolic and the fatty acids profiles by LC-MS/MS and GC/MS with the antioxidant, anticholinesterase and antimicrobial activities, and aflatoxin contents of Malva neglecta and Malvella sherardiana. The phenolic composition of M. neglecta and M. sherardiana were determined by LC-MS/MS. In studied twenty seven compounds, malic and 4-OH benzoic acids were found to be the most abundant compounds in M. neglecta and M. sherardiana, respectively. On the other hand, essential ois and fatty acids composition were determined by GC/MS analysis. It is found that total flavonoid contents in methanol extracts were less than their total phenolic contents. The methanol extracts of the plants showed the highest effect in all antioxidant assays of this study. The methanol extract of M. neglecta showed the highest activity among all of the extracts against acetyl- and butyryl- cholinesterase enzymes. The acetone extracts of M. neglacta and M. sherardiana exhibited moderate activity against C. albicans. The results of the present study is also showed that the M. neglecta and M. sherardiana can also be used as a food source due to its high phenolic acid content and good antioxidant property. Also, the samples were aflatoxin free.