Abstract

Resistance training with blood flow restriction (RTBFR) allows physically impaired people living with HIV (PWH) to exercise at lower intensities than traditional resistance training (TRT). But the acute and chronic cardiac and metabolic responses of PWH following an RTBFR protocol are unknown. The objective was to compare the safety of acute and chronic effects on hemodynamic and lipid profiles between TRT or RTBFR in PWH. In this randomized control trial, 14 PWH were allocated in RTBFR (GRTBFR; n = 7) or TRT (GTRT; n = 7). Both resistance training protocols had 36 sessions (12 weeks, three times per week). Protocol intensity was 30% (GRTBFR) and 80% (GTRT). Hemodynamic (heart rate, blood pressure) and lipid profile were acutely (rest and post exercise 7th, 22nd, and 35th sessions) and chronically (pre and post-program) recorded. General linear models were applied to determine group * time interaction. In the comparisons between groups, the resistance training program showed acute adaptations: hemodynamic responses were not different (p > 0.05), regardless of the assessment session; and chronicles: changes in lipidic profile favors GRTBFR, which significantly lower level of total cholesterol (p = 0.024), triglycerides (p = 0.002) and LDL (p = 0.030) compared to GTRT. RTBFR and TRT induced a similar hemodynamic adaptation in PWH, with no significant risks of increased cardiovascular stress. Additionally, RTBFR promoted better chronic adequacy of lipid profile than TRT. Therefore, RTBFR presents a safe resistance training alternative for PWH.

Trial registration: ClinicalTrials.gov ID: NCT02783417; Date of registration: 26/05/2016.

Details

Title
Acute and chronic cardiometabolic responses induced by resistance training with blood flow restriction in HIV patients
Author
Alves, Thiago Cândido 1   VIAFID ORCID Logo  ; Pugliesi Abdalla, Pedro 2   VIAFID ORCID Logo  ; Bohn, Lucimere 3   VIAFID ORCID Logo  ; Da Silva, Leonardo Santos Lopes 1   VIAFID ORCID Logo  ; dos Santos, André Pereira 1   VIAFID ORCID Logo  ; Tasinafo Júnior, Márcio Fernando 1   VIAFID ORCID Logo  ; Rossini Venturini, Ana Cláudia 1   VIAFID ORCID Logo  ; Mota, Jorge 4   VIAFID ORCID Logo  ; Lopes Machado, Dalmo Roberto 2   VIAFID ORCID Logo 

 Universidade de São Paulo, Ribeirão Preto, Brazil (GRID:grid.11899.38) (ISNI:0000 0004 1937 0722) 
 Universidade de São Paulo, Ribeirão Preto, Brazil (GRID:grid.11899.38) (ISNI:0000 0004 1937 0722); Universidade do Porto, Porto, Portugal (GRID:grid.5808.5) (ISNI:0000 0001 1503 7226) 
 Universidade do Porto, Porto, Portugal (GRID:grid.5808.5) (ISNI:0000 0001 1503 7226); Universidade Lusófona do Porto, Porto, Portugal (GRID:grid.410936.9) (ISNI:0000 0001 2199 9085) 
 Universidade do Porto, Porto, Portugal (GRID:grid.5808.5) (ISNI:0000 0001 1503 7226) 
Publication year
2022
Publication date
2022
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2723291871
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.