In the original article [1], there was a mistake in Table 1 as published. There were two tumors with tumor size ≤ 5 cm in the NTRK fusion group (n = 5); however, there were three tumors with tumor size ≤ 5 cm in the five cases in Table 3. Moreover, patients 0 and 1 were low- and intermediate-risk of metastasis, respectively, in Table 1, which was not consistent with the results in Table 3. The corrected Table 1 appears below. Modified numbers are red-colored.
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Baseline characteristics.
Characteristics | Total (n = 31) N (%) | NTRK Fusion (n = 5) | NTRK Wild Type (n = 26) | p-Value |
---|---|---|---|---|
Age | ||||
Median (range) | 56 (33–92) | 61 (33–92) | 53 (37–84) | 0.163 |
Sex | - | - | - | 1000 |
Male | 14 (45.2) | 2 (40.0) | 12 (46.2) | - |
Female | 17 (54.8) | 3 (60.0) | 14 (53.8) | - |
Tumor size (cm) | - | - | - | - |
Median ± SD | 8.2 ± 5.3 | 3.9 ± 6.5 | 6.0 ± 5.2 | 0.410 |
Tumor location | - | - | - | 0.028 |
Abdominal wall | 1 (0.3) | 0 (0.0) | 1 (3.8) | - |
Stomach | 14 (45.1) | 1 (20.0) | 14 (53.8) | - |
Small bowel | 11 (35.4) | 2 (40.0) | 6 (23.1) | - |
Descending colon | 1 (0.3) | 0 (0.0) | 1 (3.8) | - |
Rectum | 4 (12.9) | 2 (40.0) | 4 (15.4) | - |
Tumor size, groups (cm) ◇ | - | - | - | 1000 |
≤5 | 14 (50.0) |
|
|
- |
>5 | 14 (50.0) |
|
|
-- |
Mitotic rate ◐ (no. of mitoses/50 HPFs *) | - | - | - | 0.711 |
≤5 | 11 (50.0) | 2 (40.0) | 12 (52.2) | - |
>5 | 16 (50.0) | 3 (60.0) | 10 (43.5) | - |
Disease status | - | - | - | 0.859 |
No evidence of disease | 21 (67.7) | 5 (100.0) | 16 (61.5) | - |
on anticancer treatment | 3 (9.7) | 0 (0.0) | 3 (11.5) | - |
Unknown | 3 (9.7) | 0 (0.0) | 3 (11.5) | - |
Dead | 4 (12.9) | 0 (0.0) | 4 (15.4) | - |
Risk of metastasis ◈ | - | - | - | 0.253 |
Low | 8 (25.8) |
|
|
- |
Intermediate | 3 (9.7) |
|
|
- |
High | 17 (54.8) | 4 (80.0) | 13 (50.0) | - |
Not assessable | 3 (9.7) | 0 (0.0) | 3 (11.5) | - |
Surgical treatment | - | - | - | 1000 |
Yes | 28 (90.3) | 5 (100.0) | 23 (88.5) | - |
No | 3 (9.7) | 0 (0.0) | 3 (11.5) | - |
◇ For three inoperable cases, size information and mitotic rate are missing because there was no surgical specimen. ◐ Mitotic rate was not evaluated in one surgical specimen. ◈ Risk of metastasis was evaluated according to the National Institute of Health (NIH) classification. HPFs: high-power fields; * per 50 HPFs is a total of 5 mm2.
Reference
1. Lee, J.H.; Shin, S.-J.; Choe, E.-A.; Kim, J.; Hyung, W.J.; Kim, H.S.; Jung, M.; Beom, S.-H.; Kim, T.I.; Ahn, J.B. et al. Tropomyosin-related kinase fusions in gastrointestinal stromal tumors. Cancers; 2022; 14, 2659. [DOI: https://dx.doi.org/10.3390/cancers14112659] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/35681640]
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1 Department of Internal Medicine, Division of Medical Oncology, Eunpyeong St. Mary’s Hospital, The Catholic University of Korea, Seoul 03312, Republic of Korea
2 Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of Korea
3 Department of Internal Medicine, Division of Hospital Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
4 Department of Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
5 Department of Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
6 Yonsei Cancer Center, Department of Internal Medicine, Division of Medical Oncology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
7 Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea