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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

The subject of the current research study is aimed at the development of novel types of contrast agents (CAs) for multi-energy computed tomography (CT) based on Ln–graphene composites, which include Ln (Ln = La, Nd, and Gd) nanoparticles with a size of 2–3 nm, acting as key contrasting elements, and graphene nanoflakes (GNFs) acting as the matrix. The synthesis and surface modifications of the GNFs and the properties of the new CAs are presented herein. The samples have had their characteristics determined using X-ray photoelectron spectroscopy, X-Ray diffraction, transmission electron microscopy, thermogravimetric analysis, and Raman spectroscopy. Multi-energy CT images of the La-, Nd-, and Gd-based CAs demonstrating their visualization and discriminative properties, as well as the possibility of a quantitative analysis, are presented.

Details

Title
New Composite Contrast Agents Based on Ln and Graphene Matrix for Multi-Energy Computed Tomography
Author
Suslova, Evgeniya V 1 ; Kozlov, Alexei P 1   VIAFID ORCID Logo  ; Shashurin, Denis A 2 ; Rozhkov, Vladislav A 3   VIAFID ORCID Logo  ; Sotenskii, Rostislav V 3 ; Maximov, Sergei V 1 ; Savilov, Serguei V 1 ; Medvedev, Oleg S 4   VIAFID ORCID Logo  ; Chelkov, Georgy A 3 

 Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia 
 Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia; Faculty of Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia 
 Joint Institute for Nuclear Research, 141980 Dubna, Russia 
 Faculty of Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia; Laboratory of Experimental Pharmacology, Institute of Experimental Cardiology, National Medical Research Center of Cardiology Named after Academician E.I. Chazov, 121552 Moscow, Russia 
First page
4110
Publication year
2022
Publication date
2022
Publisher
MDPI AG
e-ISSN
20794991
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2748553274
Copyright
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.