Diaphragm neurostimulation reduces mechanical power and mitigates brain injury associated with MV and ARDS

Abstract

According to Ziaka and Exadaktylos’s review, the interaction between the patient and the ventilator might lead to brain injury due to individual susceptibility to the development of acute lung injury during MV [1]. The authors postulated that this is a consequence of a disruption in the neural control of respiration and immunological response due to lung injury associated with ARDS [1]. The review stated that one possible cause of brain injury due to ARDS is a disruption in the conversion of the mechanical stimuli produced by the pulmonary stretch receptors during MV, which in turn results in an aberrant biological signal triggering brain injury [1].