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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Diverticular disease is highly prevalent in the Western world, placing an increased burden on healthcare systems. This review clarifies the consensus in the literature on the disease’s classification, etiology, and management. Diverticular disease, caused by sac-like protrusions of colonic mucosa through the muscular colonic wall, has a varied disease course. Multiple theories contribute to our understanding of the etiology of the disease, with pathogenesis affected by age, diet, environmental conditions, lifestyle, the microbiome, genetics, and motility. The subtypes of diverticular disease in this review include symptomatic uncomplicated diverticular disease, segmental colitis associated with diverticulosis, and uncomplicated and complicated diverticulitis. We discuss emerging treatments and outline management options, such as supportive care, conservative management with or without antibiotics, and surgical intervention.

Details

Title
Diverticular Disease—An Updated Management Review
Author
Kishnani, Sujata 1   VIAFID ORCID Logo  ; Ottaviano, Kathryn 2   VIAFID ORCID Logo  ; Rosenberg, Lisa 3 ; Soe Htet Arker 4   VIAFID ORCID Logo  ; Lee, Hwajeong 4   VIAFID ORCID Logo  ; Schuster, Michael 4 ; Tadros, Micheal 5   VIAFID ORCID Logo  ; Valerian, Brian 2 

 Albany Medical College, Albany, NY 12208, USA 
 Department of Surgery, Albany Medical Center Hospital, Albany, NY 12208, USA 
 Department of Internal Medicine, Albany Medical Center Hospital, Albany, NY 12208, USA 
 Department of Pathology, Albany Medical Center Hospital, Albany, NY 12208, USA 
 Department of Gastroenterology and Hepatology, Albany Medical Center Hospital, Albany, NY 12208, USA 
First page
326
Publication year
2022
Publication date
2022
Publisher
MDPI AG
ISSN
20367414
e-ISSN
20367422
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2756698559
Copyright
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.