Correlation of cholesterol ratios and conventional isolated lipid parameters as cardiovascular risk markers to anthropometric and hemodynamic variables in healthy overweight/obese subjects

Abstract

[...]novel parameters, that is, lipid ratios are being resorted to label CV risk. Normal levels of DBP can be indicative of a combination of two inverse phenomenas, first, the increase in peripheral vascular resistance which raises DBP and second, the increase in arterial stiffness which decreases DBP, both cancelling each other resulting in a normal DBP and disguising underlying risk factors. Since arterial stiffening causes SBP to increase and DBP to decrease, the gap between the two, pulse pressure (PP), may be the best predictor of cardiac events for all the blood pressure values. [8] With this background, we can now understand that obesity associated anthropometric measures, lipid derangements, and hemodynamic changes which seem to be explicitly directly correlated may sometimes cannot be elucidated leading to a late diagnosis and hence a grave loss. [...]aiming to fill some of such knowledge gaps about the choice of markers, we planned a study on apparently healthy overweight/obese subjects in search for a reliable and early biomarker of CV risk. [...]the objective of our study was (a) to record demographic variables.