Abstract

Genetic load refers to the accumulated and potentially life-threatening deleterious mutations in populations. Understanding the mechanisms underlying genetic load variation of transposable elements (TEs), one major large-effect mutations, during range expansion is an intriguing question in biology. Here, we used 1,115 globally natural accessions of Arabidopsis thaliana, to study the driving forces of TE load variation during its range expansion. The TE load increased with range expansion, especially in the recently established Yangtze River basin population. The effective population size explained 62.0% of the variance in TE load, and high transposition rate and positive selection or hitch-hiking effect contributed to the accumulation of TEs in the expanded populations. We genetically mapped the candidate causal genes or TEs and revealed the genetic architecture of TE load. Overall, this study reveals the variation in the genetic load of TEs during Arabidopsis expansion and highlights the causes of TE load variation.

Competing Interest Statement

The authors have declared no competing interest.

Details

Title
Forces driving transposable element load variation during Arabidopsis range expansion
Author
Jiang, Juan; Yong-Chao, Xu; Zhi-Qin, Zhang; Jia-Fu, Chen; Xiao-Min, Niu; Xing-Hui Hou; Xin-Tong, Li; Wang, Li; Zhang, Yong; Song, Ge; Guo, Yalong
University/institution
Cold Spring Harbor Laboratory Press
Section
New Results
Publication year
2022
Publication date
Dec 30, 2022
Publisher
Cold Spring Harbor Laboratory Press
ISSN
2692-8205
Source type
Working Paper
Language of publication
English
ProQuest document ID
2759430130
Copyright
© 2022. This article is published under http://creativecommons.org/licenses/by/4.0/ (“the License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.