Abstract

M0 macrophages accounted for more than 9.8%, indicating a poor prognosis in pancreatic cancer.

M0 macrophages proportion were negatively correlated with CD8 + T cells, and immune scores.

M0 macrophages promote pancreatic cancer growth in vivo.

Elimination of M0 macrophages may be a promising strategy against PAAD.

Details

Title
Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation
Author
Pan-ling, Xu; Chien-shan, Cheng; Wang, Ting; Dong, Shu; Li, Ping
Pages
1-11
Section
Research
Publication year
2023
Publication date
2023
Publisher
BioMed Central
e-ISSN
14712407
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2777771397
Copyright
© 2023. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.