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Abstract
El estudio pretende comparar el rendimiento de pacientes, diagnosticados de enfermedad de Alzheimer temprana (EA) y depresión mayor unipolar (D), con un grupo de sujetos sanos control (SC) en diferentes tareas de memoria no verbal (MNV), recuerdo de posición y reconocimiento de dibujos abstractos. Todos los participantes completaron un protocolo integral para el diagnóstico de la demencia. Los pacientes con EA (n= 27) y depresión unipolar (n= 19) fueron comparados con el grupo SC (n= 30) en un test estandarizado de aprendizaje visoespacial. Los pacientes con EA rindieron significativamente más bajo en MNV en comparación con el grupo SC y D, pero no hubo diferencias entre EA y D en el recuerdo de posición. Asimismo, el grupo de EA no mostró una tasa de olvido mayor en el recuerdo de posición o reconocimiento de dibujos en comparación con los grupos SC y D. Estos resultados son interpretados en función de los procesos neurocognitivos que explican el deterioro de la MNV en la EA y la depresión.
Non-verbal memory impairment in Alzheimer-type dementia: Forgetting or acquisition? The research aims to compare patients diagnosed with early Alzheimer’s disease (AD) and unipolar major depression (D) with a healthy control group (HS) on diverse nonverbal memory tasks (NVM), recall of position, and recognition of abstracts designs. All participants completed a global protocol for diagnosis of dementia. The patients with early AD (n= 27) and D (n= 19) were compared with the healthy subject group (n= 30) on a standardised visuospatial learning test. The AD patients scored significantly lower than HS and D on NVM tasks, but there were no significant differences between AD and D on position recall. Furthermore, the AD group did not show faster forgetting rates on position recall or design recognition in comparison to HS and D groups. These results are interpreted in terms of neurocognitive processes that explain NVM impairment in AD and depression.
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