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Abstract
Background
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation.
Aim
This study was carried out to evaluate the level of vitamin D and immunoglobulin E (IgE) in asthmatic patients during exacerbation and after remission.
Patients and methods
This study was carried out on 30 patients with bronchial asthma diagnosed and classified according to Global Initiative for Asthma 2015 and 20 healthy individuals. Serum vitamin D and IgE were measured using enzyme-linked immunosorbent assay for all participants.
Results
Vitamin D level was highly significantly lower in the asthmatic group during exacerbation compared with the asthmatic group after remission and the control group, and the total IgE level was highly significantly higher in the asthmatic groups compared with the control group.
Conclusion
Asthmatic patients might have an increased risk of having vitamin D deficiency during exacerbation and after remission, whereas the levels of serum total IgE level was high in asthmatic patients compared with normal individuals.
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Details
1 Benha University Hospital, Department of Chest, Banha, Egypt (GRID:grid.411660.4) (ISNI:0000 0004 0621 2741)
2 Kafr Ahokr Hospital, Department of Chest, Benha, Egypt (GRID:grid.411660.4)
3 Benha University Hospital, Department of Clinical and Chemical Pathology, Banha, Egypt (GRID:grid.411660.4) (ISNI:0000 0004 0621 2741)