Abstract
To the Editor: Upfront autologous stem cell transplantation (ASCT) has been an integral part of the management of young and eligible older patients with newly diagnosed multiple myeloma (NDMM) for over three decades. PFS and OS were calculated using the Kaplan–Meier method, and log-rank tests with 95% confidence intervals (95% CIs) were used to compare time-dependent outcome measures. In this study, there was no significant difference in PFS and OS based on ISS stage and cytogenetic risk, indicating that high-risk patients could benefit from tandem transplantation. [...]our study also demonstrated low toxicity of tandem ASCT in real-world patients, with a 100-day TRM of 0%.
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Details
1 Department of Hematology, Hematopoietic Stem Cell Transplantation Center, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China
2 Department of Hematology, Hematopoietic Stem Cell Transplantation Center, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China; Translational Medicine Center on Hematology, Fujian Medical University, Fuzhou, Fujian 350001, China