Abstract

The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.

Details

Title
Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data
Author
Díaz, Natalia A. 1 ; de Miguel, Rosa 2 ; Agüero, Fernando 3 ; Sued, Omar 4 ; Arribas, José R. 2 ; Ambrosioni, Juan 5   VIAFID ORCID Logo  ; Blanco, José L.; de la Mora, Lorena; García-Alcaide, Felipe; González-Cordón, Ana; Inciarte, Alexis; Laguno, Montserrat; Leal, Lorna; Martínez-Chamorro, Esteban; Martínez-Rebollar, María; Miró, José M.; Rojas, Jhon F.; Torres, Berta; Mallolas, Josep; Albiac, Laia; Agüero, Daiana L.; Bodro, Marta; Cardozo, Celia; Chumbita, Mariana; García, Nicol; García-Vidal, Carolina; Hernández-Meneses, Marta M.; Herrera, Sabina; Linares, Laura; Moreno, Antonio; Morata, Laura; Martínez-Martínez, Jose A.; Puerta, Pedro; Rico, Verónica; Soriano, Alex; Martínez, Mikel; del Mar Mosquera, María; Marcos, María A.; Vila, Jordi; Tuset, Montse; Soy, Dolors; Vilella, Anna; Almuedo, Alex; Pinazo, María J.; Muñoz, José

1  Hospital Cuenca Alta, Infectious Diseases Service, Cañuelas, Argentina 
2  Hospital Universitario La Paz, Infectious Diseases Unit, Madrid, Spain (GRID:grid.81821.32) (ISNI:0000 0000 8970 9163) 
3  Hospital Universitario Bellvitge, Preventive Medicine Service, Barcelona, Spain (GRID:grid.411129.e) (ISNI:0000 0000 8836 0780) 
4  Fundación Huésped, Buenos Aires, Argentina (GRID:grid.491017.a) (ISNI:0000 0004 7664 5892) 
5  Hospital Clinic-IDIBAPS, HIV Unit and Infectious Diseases Service, Barcelona, Spain (GRID:grid.410458.c) (ISNI:0000 0000 9635 9413) 
Pages
1-13
Publication year
2022
Publication date
Feb 2022
Publisher
Springer Nature B.V.
ISSN
21938229
e-ISSN
21936382
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1007/s40121-021-00547-y
ProQuest document ID
2867114383
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.