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Abstract
Cardiovascular disease (CVD) is one of the leading causes of premature retirement. However, the relationship between CVD risk factors and workforce participation is not well known. We studied the relationship between midlife CVD risk, age at retirement, work-loss years, and survival in retirement. Middle-aged Finnish men (initial n = 3490, mean age = 47.8 years) were assessed for CVD risk factors and general health in the 1970s. They worked as business executives and provided information on their retirement status in the year 2000. Survival was followed up to the 9th decade of life with a follow-up of up to 44 years. Work-loss years were calculated as death or retirement occurring at age ≤ 65 years. Smoking, body mass index, and alcohol use were used as covariates, excluding models of CVD risk, which were adjusted for alcohol use only. Higher risk of 10-year fatal CVD was associated with 0.32 more years (relative risk < 1 vs. 1, covariate-adjusted β = 0.32, 95% CI = 0.13, 0.53) of work-loss. Higher risk of 5-year incident (covariate-adjusted time-constant HR = 1.32, 95% CI = 1.19, 1.47) and 10-year fatal (covariate-adjusted time-dependent HR = 1.55, 95% CI = 1.30, 1.85) CVD in midlife were associated with fewer years spent in retirement. Poorer self-rated health and physical fitness and higher levels of triglycerides were associated with increased hazard of earlier retirement, more work-loss years, and fewer years spent in retirement. Poorer health and greater midlife CVD risk may be associated with earlier exit from the workforce and fewer years spent in retirement. Management of CVD risk in midlife may support people to work longer.
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1 University of Helsinki and Helsinki University Hospital, Department of General Practice and Primary Health Care, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071); Folkhälsan Research Centre, Helsinki, Finland (GRID:grid.428673.c) (ISNI:0000 0004 0409 6302); Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden (GRID:grid.4714.6) (ISNI:0000 0004 1937 0626)
2 University of Jyväskylä, Gerontology Research Center and Faculty of Sport and Health Sciences, Jyväskylä, Finland (GRID:grid.9681.6) (ISNI:0000 0001 1013 7965)
3 University of Jyväskylä, Management and Leadership, Jyväskylä University School of Business and Economics, Jyväskylä, Finland (GRID:grid.9681.6) (ISNI:0000 0001 1013 7965)
4 University of Helsinki and Helsinki University Hospital, Department of Medicine, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071)
5 University of Helsinki and Helsinki University Hospital, Department of Medicine, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071); University of Oulu, Centre for Life Course Health Research, Oulu, Finland (GRID:grid.10858.34) (ISNI:0000 0001 0941 4873)
6 Folkhälsan Research Centre, Helsinki, Finland (GRID:grid.428673.c) (ISNI:0000 0004 0409 6302); University of Jyväskylä, Gerontology Research Center and Faculty of Sport and Health Sciences, Jyväskylä, Finland (GRID:grid.9681.6) (ISNI:0000 0001 1013 7965)