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© 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

In patients with drug-resistant epilepsy who are considering surgery, intracranial EEG (iEEG) helps delineate the putative epileptogenic zone. In a minority of patients, iEEG fails to identify seizure onsets. In such cases, it might be worthwhile to reimplant more iEEG electrodes. The consequences of such a strategy for the patient are unknown. We matched 12 patients in whom the initially implanted iEEG electrodes did not delineate the seizure onset zone precisely enough to offer resective surgery, and in whom additional iEEG electrodes were implanted during the same inpatient stay, to controls who did not undergo reimplantation. Seven cases and eight controls proceeded to resective surgery. No intracranial infection occurred. One control suffered an intracranial hemorrhage. Three cases and two controls suffered from a post-operative neurological or neuropsychological deficit. We found no difference in post-operative seizure control between cases and controls. Compared to an ILAE score of 5 (ie, stable seizure frequency in the absence of resective surgery), cases showed significant improvement. Reimplantation of iEEG electrodes can offer the possibility of resective epilepsy surgery to patients in whom the initial iEEG investigation was inconclusive, without compromising on the risk of complications or seizure control.

Details

Title
Implantation and reimplantation of intracranial EEG electrodes in patients considering epilepsy surgery
Author
Eelbode, Céline 1 ; Spinelli, Laurent 1   VIAFID ORCID Logo  ; Corniola, Marco 2   VIAFID ORCID Logo  ; Shahan Momjian 3 ; Seeck, Margitta 1 ; Schaller, Karl 3 ; Mégevand, Pierre 1   VIAFID ORCID Logo 

 Neurology division, Geneva University Hospitals, Geneva, Switzerland; Clinical Neuroscience Department, University of Geneva, Faculty of Medicine, Geneva, Switzerland 
 Clinical Neuroscience Department, University of Geneva, Faculty of Medicine, Geneva, Switzerland; Neurosurgery Division, Geneva University Hospitals, Geneva, Switzerland; Neurosurgery Division, Rennes University Hospital, Rennes, France; INSERM UMR 1099 LTSI, University of Rennes, Rennes, France 
 Clinical Neuroscience Department, University of Geneva, Faculty of Medicine, Geneva, Switzerland; Neurosurgery Division, Geneva University Hospitals, Geneva, Switzerland 
Pages
1622-1627
Section
SHORT RESEARCH ARTICLES
Publication year
2023
Publication date
Dec 2023
Publisher
John Wiley & Sons, Inc.
e-ISSN
24709239
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2895664310
Copyright
© 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.