Abstract

Boron neutron capture therapy (BNCT) is a high-dose-intensive radiation therapy that has gained popularity due to advancements in accelerator neutron sources. To determine the dose for BNCT, it is necessary to know the difficult-to-determine boron concentration and neutron fluence. To estimate this dose, we propose a method of measuring the prompt γ-rays (PGs) from the boron neutron capture reaction (BNCR) using a Compton camera. We performed a fundamental experiment to verify basic imaging performance and the ability to discern the PGs from 511 keV annihilation γ-rays. A Si/CdTe Compton camera was used to image the BNCR and showed an energy peak of 478 keV PGs, separate from the annihilation γ-ray peak. The Compton camera could visualize the boron target with low neutron intensity and high boron concentration. This study experimentally confirms the ability of Si/CdTe Compton cameras to image BNCRs.

Details

Title
Experimental study on Compton camera for boron neutron capture therapy applications
Author
Sakai, M. 1 ; Tamaki, S. 2 ; Murata, I. 2 ; Parajuli, R. K. 3 ; Matsumura, A. 1 ; Kubo, N. 1 ; Tashiro, M. 1 

 Gunma University Heavy Ion Medical Center, Maebashi, Japan (GRID:grid.256642.1) (ISNI:0000 0000 9269 4097) 
 Osaka University, Graduate School of Engineering, Osaka, Japan (GRID:grid.136593.b) (ISNI:0000 0004 0373 3971) 
 Gunma University Heavy Ion Medical Center, Maebashi, Japan (GRID:grid.256642.1) (ISNI:0000 0000 9269 4097); The University of Sydney, Sydney Imaging Core Research Facility, Camperdown, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
Pages
22883
Publication year
2023
Publication date
2023
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2904483479
Copyright
© The Author(s) 2023. corrected publication 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.