Abstract

SEE PDF] No specific patient or disease (age, sex, performance status, measurable residual disease level, white blood cell count, neutrophils and lymphocytes count, nervous system infiltration, previous allogenous stem cell transplantation, c-reactive protein level) characteristics were significantly associated with LTC occurrence. Life-threatening events occurred in 9% of B-ALL patients treated with blinatumomab in our cohort, necessitating ICU admission in 7% of the cases, which compares favorably with the rate observed after intensive chemotherapy (17.5%) [4] or CAR-T cells (32%) [5]. Availability of data and materials The datasets used and/or analyzed in the current study are available from the corresponding author on reasonable request.

Details

Title
Life-threatening complications and intensive care unit management in patients treated with blinatumomab for B-cell acute lymphoblastic leukemia
Author
Urbino, Irene; Lengliné, Etienne; Valade, Sandrine; Cerrano, Marco; Sebert, Marie; Raffoux, Emmanuel; Rabian, Florence; Azoulay, Elie; Boissel, Nicolas
Pages
1-3
Section
Correspondence
Publication year
2024
Publication date
2024
Publisher
BioMed Central
ISSN
13648535
e-ISSN
1366609X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2914284312
Copyright
© 2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.