Abstract

Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes. Additionally, ambiguous clinical indications for root canal medication and non-standardized dressing protocols must be clarified. Inappropriate intracanal medication may present side effects and jeopardize the therapeutic outcomes. Indeed, clinicians have been aware of these concerns for years. Based on the current evidence of studies, this article reviews the properties of various irrigants and intracanal medicaments and elucidates their effectiveness and interactions. The evolution of different kinetic irrigation methods, their effects, limitations, the paradigm shift, current indications, and effective operational procedures regarding intracanal medication are also discussed. This expert consensus aims to establish the clinical operation guidelines for root canal irrigation and a position statement on intracanal medication, thus facilitating a better understanding of infection control, standardizing clinical practice, and ultimately improving the success of endodontic therapy.

Details

Title
Expert consensus on irrigation and intracanal medication in root canal therapy
Author
Zou, Xiaoying 1 ; Zheng, Xin 2   VIAFID ORCID Logo  ; Liang, Yuhong 3 ; Zhang, Chengfei 4 ; Fan, Bing 5 ; Liang, Jingping 6 ; Ling, Junqi 7 ; Bian, Zhuan 5 ; Yu, Qing 8 ; Hou, Benxiang 9 ; Chen, Zhi 5   VIAFID ORCID Logo  ; Wei, Xi 7   VIAFID ORCID Logo  ; Qiu, Lihong 10 ; Chen, Wenxia 11 ; He, Wenxi 12 ; Xu, Xin 2   VIAFID ORCID Logo  ; Meng, Liuyan 5 ; Zhang, Chen 13 ; Chen, Liming 14 ; Deng, Shuli 15 ; Lei, Yayan 16 ; Xie, Xiaoli 17 ; Wang, Xiaoyan 18 ; Yu, Jinhua 19   VIAFID ORCID Logo  ; Zhao, Jin 20 ; Shen, Song 21 ; Zhou, Xuedong 2 ; Yue, Lin 18 

1  Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Department of Cariology and Endodontology, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319); Center of Stomatology, Peking University Hospital, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
2  Sichuan University, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Chengdu, China (GRID:grid.13291.38) (ISNI:0000 0001 0807 1581) 
3  Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Department of Emergency, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
4  The University of Hong Kong, Restorative Dental Sciences, Endodontics, Faculty of Dentistry, Hong Kong SAR, China (GRID:grid.194645.b) (ISNI:0000 0001 2174 2757) 
5  Wuhan University, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan, China (GRID:grid.49470.3e) (ISNI:0000 0001 2331 6153) 
6  Shanghai Jiao Tong University; National Clinical Research Center for Oral Diseases; National Center for Stomatology; Shanghai Key Laboratory of Stomatology, Department of Endodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai, China (GRID:grid.16821.3c) (ISNI:0000 0004 0368 8293) 
7  Sun Yat-Sen University & Guangdong Provincial Key Laboratory of Stomatology , Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Guangzhou, China (GRID:grid.452802.9) 
8  The Fourth Military Medical University, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Oral Diseases, Department of Operative Dentistry & Endodontics, School of Stomatology, Xián, China (GRID:grid.233520.5) (ISNI:0000 0004 1761 4404) 
9  Capital Medical University, Center for Microscope Enhanced Dentistry, Beijing Stomatological Hospital, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X) 
10  China Medical University, Department of Endodontics, School of Stomatology, Shenyang, China (GRID:grid.254145.3) (ISNI:0000 0001 0083 6092) 
11  Guangxi Medical University, College & Hospital of Stomatology, Nanning, China (GRID:grid.256607.0) (ISNI:0000 0004 1798 2653) 
12  The Air Force Medical University, Department of Stomatology, Air Force Medical Center, Beijing, China (GRID:grid.233520.5) (ISNI:0000 0004 1761 4404) 
13  Capital Medical University, Department of Endodontics, Beijing Stomatological Hospital, School of Stomatology, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X) 
14  Guiyang Stomatological Hospital, Department of Endodontics, Guiyang, China (GRID:grid.24696.3f) 
15  Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou, China (GRID:grid.452802.9) 
16  the Affiliated Stomatological Hospital of Kunming Medical University, Department of Endodontics, Kunming, China (GRID:grid.285847.4) (ISNI:0000 0000 9588 0960) 
17  Central South University, Department of Endodontology, Hunan Xiangya Stomatological Hospital, Changsha, China (GRID:grid.216417.7) (ISNI:0000 0001 0379 7164) 
18  Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Department of Cariology and Endodontology, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
19  Nanjing Medical University, Institute of Stomatology, Nanjing Medical University & Department of Endodontics, Affiliated Hospital of Stomatology, Nanjing, China (GRID:grid.89957.3a) (ISNI:0000 0000 9255 8984) 
20  The First Affiliated Hospital of Xinjiang Medical University, Department of Endodontics, Urumqi, China (GRID:grid.412631.3) 
21  Center of Stomatology, Peking University Hospital, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
Pages
23
Publication year
2024
Publication date
2024
Publisher
Springer Nature B.V.
ISSN
16742818
e-ISSN
20493169
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41368-024-00280-5
ProQuest document ID
2933662157
Copyright
© The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.