Abstract

A new alkaloid called Litsine E (1) and three known aporphine alkaloids (2-4) were isolated from Litsea glutinosa. The structure of the new compound was established using spectroscopic techniques such as HMBC, HSQC, COSY, NOESY, and HRESIMS. Electronic circular dichroism (ECD) calculations were used to estimate its absolute configuration. Subsequently, the newly identified compound was evaluated for its potential to attenuate palmitate-induced viability, demonstrating a significant increase in viability in MIN6 cells.

Details

Title
A New Aporphine Alkaloid from Litsea glutinosa to Attenuate Palmitate Induced Viability in MIN6 Cells
Author
Zhou, Yuanyuan  VIAFID ORCID Logo  ; Huang, Zibao  VIAFID ORCID Logo  ; Liu, Chenpeng  VIAFID ORCID Logo  ; Li, Guoyu  VIAFID ORCID Logo  ; Zhang, Xiaopo  VIAFID ORCID Logo 
Pages
155-160
Section
Original Article
Publication year
2024
Publication date
Jan-Feb 2024
Publisher
ACG Publications
e-ISSN
13076167
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.25135/rnp.427.2308.2875
ProQuest document ID
2954786754
Copyright
© 2024. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at http://www.acgpubs.org/journal/records-of-natural-products/advisory-board