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Abstract
Computational fluid dynamics (CFD) has been utilized to calculate hemodynamic parameters in anterior communicating artery aneurysm (AComA), which is located at a junction between left and right A1 and A2 segments. However, complete or half circle of Willis (CoW) models are used indiscriminately. This study aims to suggest recommendations for determining suitable CoW model. Five patient-specific CoW models with AComA were used, and each model was divided into complete, left-half, and right-half models. After validating the CFD using a flow experiment, the hemodynamic parameters and flow patterns in five AComAs were compared. In four out of five cases, inflow from one A1 side had a dominant influence on the AComA, while both left and right A1 sides affected the AComA in the remaining case. Also, the average difference in time-averaged wall shear stress between the complete and half models for four cases was 4.6%, but it was 62% in the other case. The differences in the vascular resistances of left and right A1 and A2 segments greatly influenced the flow patterns in the AComA. These results may help to enhance clinicians’ understanding of blood flow in the brain, leading to improvements in diagnosis and treatment of cerebral aneurysms.
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Details
1 Hanyang University, Department of Mechanical Engineering and BK21 FOUR ERICA-ACE Center, Ansan, Korea (GRID:grid.49606.3d) (ISNI:0000 0001 1364 9317)
2 Yonsei University, Yongin Severance Hospital, Department of Neurosurgery, College of Medicine, Yongin, Korea (GRID:grid.15444.30) (ISNI:0000 0004 0470 5454)
3 Yonsei University, Severance Hospital, Department of Neurosurgery, College of Medicine, Seoul, Korea (GRID:grid.415562.1) (ISNI:0000 0004 0636 3064)
4 Yonsei University, Severance Hospital, Department of Neurosurgery, College of Medicine, Seoul, Korea (GRID:grid.415562.1) (ISNI:0000 0004 0636 3064); Korea University, Department of Anatomy, Graduate School of Medicine, Seoul, Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678)