Abstract

The baseline SCr level was defined as the lowest SCr recorded during hospitalization or was based on the age- and sex-standardized SCr reference value for the Chinese population. Variables Overall Non-AKI AKI P values Donors n 139 81 58 – Age (months) 30.7 (12.0, 78.2) 30.7 (12.0, 78.0) 30.1 (12.0, 79.0) 0.680 Gender Male 81 (58.3) 46 (56.8) 35 (60.3) 0.675 Female 58 (41.7) 35 (43.2) 23 (39.7) Height (cm) 90 (76.0, 120.0) 90 (76.5, 120.0) 89 (75.0, 120.9) 0.964 Body weight (kg) 12.5 (10.0, 20.0) 13.0 (10.0, 20.0) 12.0 (9.9, 20.3) 0.652 eGFR (mL·min–1·1.73m–2) 106.5 (64.1, 170.3) 130.5 (102.1, 194.7) 61.4 (40.2, 84.4) <0.001 Donor type DBD 97 (69.8) 58 (71.6) 39 (67.2) 0.581 DCD* 42 (30.2) 23 (28.4) 19 (32.8) CIT (h) 10.0 (7.5, 14.0) 10.0 (7.8, 14.0) 9.5 (7.0, 14.1) 0.718 Recipient n 197 112 85 – Age at Tx (years) 10.5 ± 4.0 10.2 ± 3.9 10.8 ± 4.1 0.335 Gender Male 95 (48.2) 45 (40.2) 50 (58.8) 0.009 Female 102 (51.8) 67 (59.8) 35 (41.2) Height (cm) 130.0 ± 23.4 128.6 ± 22.6 131.8 ± 24.3 0.342 Body weight (kg) 27.6 ± 11.8 26.7 ± 10.9 28.7 ± 12.9 0.256 Prior Tx 12 (6.1) 7 (6.3) 5 (5.9) 0.915 HLA mismatch 5 (4, 6) 5 (4, 6) 5 (5, 6) 0.197 Pre-Tx PRA ≥10% 7 (3.6) 5 (4.5) 2 (2.4) 0.701 Sex-matched 99 (50.3) 46 (41.1) 53 (62.4) 0.003 Follow-up time (months) 44.8 (35.8, 57.8) 44.7 (36.2, 53.0) 45.6 (35.1, 63.1) 0.415 Data were presented as median (IQR), n (%), or mean ± standard deviation. *Including 8 (5.8%), 5 (6.2%), and 3 (5.2%) DBCD, respectively. No significant difference was observed between the AKI and non-AKI groups in terms of the incidence (3.5% [AKI] vs. 3.6% [non-AKI], P = 0.837) or timing (log-rank test, P = 0.458) of vascular thrombotic events. In this retrospective longitudinal cohort study with a median follow-up of approximately four years, we found that utilizing pediatric AKI donor kidneys did not result in reduced short-term

Details

Title
Outcomes in pediatric recipients of single kidney transplantation from pediatric donors with acute kidney injury: A single-center pilot study
Author
Zhang, Qiang 1 ; Chen Yanxu 1 ; Yu Haiyue 2 ; Li, Jun 1 ; Wu, Chenglin 1 ; Long Sizhe 3 ; Li Pengan 3 ; Fu Qian 1 ; Zhang Huanxi 1 ; Su Xiaojun 1 ; Bowen, Xu 1 ; Liu Longshan 1 ; Wang, Changxi 4 

 Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China 
 Stomatological Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China 
 Center for Information Technology and Statistics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China 
 Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Guangzhou, Guangdong 510080, China; Guangdong Provincial Key Laboratory Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), Guangzhou, Guangdong 510080, China 
Pages
1489-1491
Section
Correspondence
Publication year
2024
Publication date
Jun 2024
Publisher
Lippincott Williams & Wilkins Ovid Technologies
ISSN
03666999
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3069662149
Copyright
Copyright © 2024 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0 (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.