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Abstract
The risk of venous thromboembolism (VTE) increases with age. However, the risk of VTE in the setting of long-term care hospitals is understudied. Our objective was to provide data on the prevalence and incidence of VTE in older adults admitted to long-term care hospitals. In this retrospective cohort study, we collected data about chronically ill and multimorbid patients aged 65 years and older from two long-term care hospitals. The primary endpoint of this study was the lifetime prevalence of VTE, and the secondary endpoint was VTE incidence during residency in long-term care hospitals. We analysed data from 1148 patients with a mean age of 84.1 ± 7.9 years, of whom 74.2% were women. The lifetime prevalence of VTE at baseline was 9.6% (95% CI 7.9–11.4). Cumulative incidence of VTE at 1, 2, and 3 years from baseline was estimated at 3.5% (95% CI 2.5–4.7), 4.2% (95% CI 3.1–5.5), and 5.4% (95% CI 4.1–7.0), respectively. Overall, the incidence rate of VTE in our study was 2.82 (95% CI 2.18–3.66) per 100 person-years. The study indicated a considerably high lifetime prevalence and incidence of VTE during residence in long-term care hospital settings, requiring further evaluation in larger prospective studies.
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1 University for Continuing Education Krems, Department for Evidence-Based Medicine and Evaluation, Krems, Austria (GRID:grid.15462.34) (ISNI:0000 0001 2108 5830)
2 Medical University of Vienna, Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Vienna, Austria (GRID:grid.22937.3d) (ISNI:0000 0000 9259 8492)
3 Haus der Barmherzigkeit Seeboeckgasse, Vienna, Austria (GRID:grid.22937.3d)
4 Haus der Barmherzigkeit Tokiostraße, Vienna, Austria (GRID:grid.22937.3d)
5 Haus der Barmherzigkeit Seeboeckgasse, Vienna, Austria (GRID:grid.22937.3d); Haus der Barmherzigkeit Tokiostraße, Vienna, Austria (GRID:grid.22937.3d); University for Continuing Education Krems, Center for Geriatric Medicine and Geriatric Nursing, Krems, Austria (GRID:grid.15462.34) (ISNI:0000 0001 2108 5830)
6 University Hospital St. Poelten, Department of Internal Medicine 3, St. Poelten, Austria (GRID:grid.459695.2); Karl Landsteiner University of Health Sciences, Krems, Austria (GRID:grid.459693.4) (ISNI:0000 0004 5929 0057)
7 University for Continuing Education Krems, Department for Evidence-Based Medicine and Evaluation, Krems, Austria (GRID:grid.15462.34) (ISNI:0000 0001 2108 5830); RTI International, Center for Public Health Methods, Research Triangle Park, USA (GRID:grid.62562.35) (ISNI:0000 0001 0030 1493)
8 Medical University of Vienna, Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Vienna, Austria (GRID:grid.22937.3d) (ISNI:0000 0000 9259 8492); Sechenov First Moscow State Medical University (Sechenov University), Department of Obstetrics, Gynecology and Perinatal Medicine, I. M., Moscow, Russia (GRID:grid.448878.f) (ISNI:0000 0001 2288 8774)