Compromised heat loss leads to a delayed ice slurry induced reduction in heat storage

Abstract

Compromised heat loss due to limited convection and evaporation can increase thermal strain. We aimed to determine the effectiveness of ice slurry ingestion to reduce thermal strain following hyperthermia in a state of compromised heat loss. Twelve healthy males (age: 25 ± 4y) underwent hot water immersion to elevate rectal temperature (T_rec) by 1.82 ± 0.08°C on four occasions. In the subsequent 60-min of seated recovery, participants ingested either 6.8 g·kg^-1 of ice slurry (-0.6°C) or control drink (37°C) in ambient conditions (21 ± 1°C, 39 ± 10% relative humidity), wearing either t-shirt and shorts (2 trials: ICE and CON) or a whole-body sweat suit (2 trials: ICE-SS and CON-SS). T_rec and mean skin temperature (T_sk) were recorded and a two-compartment thermometry model of heat storage was calculated. Heat storage was lower in ICE compared with CON at 20-40min (p ≤ 0.044, d ≥ 0.88) and for ICE-SS compared with CON-SS at 40–60 min (p ≤ 0.012, d ≥ 0.93). T_rec was lower in ICE compared with CON from 30-60min (p ≤ 0.034, d ≥ 0.65), with a trend for a reduced T_rec in ICE-SS compared with CON-SS at 40min (p = 0.079, d = 0.60). A greater T_sk was found in ICE-SS and CON-SS compared with ICE and CON (p < 0.001, d ≥ 3.37). A trend for a lower T_sk for ICE compared with CON was found at 20-40min (p ≤ 0.099, d ≥ 0.53), no differences were found for ICE-SS vs CON-SS (p ≥ 0.554, d ≤ 0.43). Ice slurry ingestion can effectively reduce heat storage when heat loss through convection and evaporation is compromised, relevant to those wearing personal protective equipment or those with compromised sweat loss. Compromised heat loss delays the reduction in heat storage, possibly related to ice slurry ingestion not lowering T_sk.

Introduction

Elevations in core temperature (T_core) and heat storage can result from exposure to hot and/or humid environments and can be further increased by metabolic heat production [1]. This thermal strain can be amplified if heat loss is reduced due to clothing, such as personal protective equipment (PPE), inhibiting convection and/or sweat evaporation [2, 3]. Similarly, disruptions to neural pathways, as found in persons with a spinal cord injury [4], impair central sudomotor and vasomotor control and sweating below the level of lesion [5], affecting heat loss [6]. Elevated T_core can impact exercise performance and recovery, including deterioration of physical capacity [7], deterioration in cognitive function [8, 9] or heat related illness [10]. These negative aspects resulting from hyperthermia can be mitigated by cooling strategies, such as cold water immersion or ice vests, which can effectively lower T_core [11]. However, the practicalities of such strategies (e.g., time availability, equipment costs, safety in certain populations, and accessibility) limit their use in applied settings.

In the context of sport and exercise performance, increasing body temperature, for example achieved via a warm-up, can enhance performance [12]. However, exceeding an optimal body temperature can limit performance [7]. Internal cooling by ice slurry ingestion has become a popular method to attenuate increases in T_core prior to (pre-cooling) and during (per-cooling) exposure to hot and humid environments and/or exercise [13–15]. However, the effectiveness of ice slurry ingestion as a strategy to reduce T_core in a hyperthermic state is under debate. On the one hand, half-time cooling [16] and cooling when in a hyperthermic state (T_core >39.6°C) [10] can decrease T_core and improve repeated sprint performance in the heat. Conversely, Iwata et al. reported that ice slurry ingestion does not alter T_core when administered at a (lower) T_core of 38.5°C [17]. Differences in study design, such as ice slurry dosage and timing, should be noted. For example, Naito et al. employed an intermittent sprint protocol where ice slurry was ingested throughout [16], whereas Iwata et al. gave one bolus at the end of a continuous exercise bout aimed at inducing hyperthermia [17]. However, they further provide a suggestion for a mechanistic explanation, arguing that the lack of a cooling effect may lie in ice slurry ingestion hindering the sweat response [17], thus blunting evaporative cooling potential [18, 19], and therefore not significantly affecting heat balance. This may hence mean that ice slurry ingestion could be most effective when sweating does not contribute to cooling, as in such conditions it would not offset the (non-existing) cooling effect of sweat evaporation. Ice slurry ingestion might therefore be of particular interest in situations in which the effect of evaporative cooling is limited.

Few studies have investigated the efficacy of ice slurry ingestion to reduce thermal strain when heat loss mechanisms are compromised. Per-cooling using ice slurry reduced gastrointestinal temperature at lower, but not moderate, exercise intensities when wearing a raincoat restricting heat loss in normothermic conditions [20], whilst ice slurry ingestion reduced T_core in participants wearing firefighting PPE during a 30-minute walk in hot conditions [21]. However, ingesting slurries during an activity may not always be feasible or practical in both sporting or professional contexts, and the efficacy of ice slurries to reduce thermal strain in the recovery of hyperthermia when heat loss is compromised remains to be explored.

Therefore, the aim of the present study was to assess the cooling effectiveness of ice slurry ingestion in a state of compromised heat loss, induced by wearing a whole-body sweat suit following passive heat exposure. We assumed that ice slurry ingestion would significantly reduce thermal strain in a state of compromised heat loss when compared with a state of normal heat loss.

Methods

Ethical approval

All experimental procedures were granted by the Loughborough University ethics committee, which were in line with the Declaration of Helsinki (review reference: 2020-1208-2037). Participants provided written informed consent and completed a health screening questionnaire prior to participating in any experimental procedures.

Participants

Between 16th March 2021 - 2^nd June 2021, twelve male able-bodied participants volunteered to take part in the study (age: 25 ± 4 y, body mass: 84.5 ± 6.6 kg, stature: 181.6 ± 7.2 cm, body mass index: 25.7 ± 2.5 kg·m^-2, sum of 8 skinfolds: 91.4 ± 28.4 mm). Participants were asked to refrain from alcohol consumption or partaking in any strenuous activity 24 h prior to each visit and were asked to maintain a consistent routine during the day before each visit. A 24-h food diary was completed prior to the first visit, and the diet was replicated for subsequent visits.

Experimental design

Four experimental trials were separated by at least 48 h in a randomized, counterbalanced order. During each trial, participants were passively immersed in hot water maintained at ~39.5°C controlled by four thermistors (Grant Instruments, Cambridge, UK) placed at the top and bottom of the immersion bath. Before participants entered the hot water bath, they were instrumented, and baseline measures were collected after 30 min of seated rest. Participants were immersed in the bath until the target T_core was reached (1.85°C change from baseline (n = 10) or an absolute value of 39.35°C if this came first (ethical limit, n = 2)), total immersion duration of was 58.2 ± 11.2 min. This was followed by a 60-min recovery phase consisting of passive seated rest in ambient conditions (20.9 ± 1.2°C, 39 ± 10% relative humidity, RH) which did not differ between trials (p = 0.966, p = 0.795 for temperature and RH respectively). Upon exiting the bath, participants rested seated and received two unflavoured aliquots (totalling 6.8 g·kg^-1) of either ice slurry drink (-0.6 ± 0.1°C; ICE) or a thermoneutral control drink (water at 37.0 ± 0.3°C; CON) to ingest within 15 minutes at 5 and 20 min of the recovery phase. To produce the ice slurry drink, small cubes of ice were blended with water (4°C). This post bath rest period was performed wearing shorts and T-shirt, creating a condition of uncompromised heat loss, or a sweat suit (SS), creating a condition of compromised heat loss. The SS was made with 98% polyester and 2% nylon and was available in three sizes, to fit the participants and only left feet, hands and the head exposed. The combination of drink type and clothing worn resulted in four conditions: ice slurry, no SS (ICE), control drink, no SS (CON), ice slurry, SS (ICE-SS), control drink, SS (CON-SS).

Physiological assessments

Participants provided a urine sample upon arrival to the laboratory, which was analysed for osmolality using a hand-held portable analyser (Osmocheck, ViTech Scientific, UK) to confirm adequate hydration prior to commencing each trial. After that, for one of four of the trials, participants’ skin fold thickness (mm) was taken from 8 sites (bicep, tricep, subscapularis, iliac crest, supraspinale, abdominal, thigh, calf) by a certified International Society for the Advancement of Kinanthropometry (ISAK) practitioner.

Rectal temperature (T_rec) was recorded with a probe that was self-inserted 10 cm beyond the anal sphincter (YSI 400 series; YSI, Yellow Springs, USA), skin temperature (T_sk) was recorded using iButtons (DS1922T, Maxim Integrated Products Inc., USA) placed on the forehead, bicep, chest, front thigh and medial calf to estimate mean T_sk respectively [22]. Heat storage was calculated using the following formula [23]:where c_b is the specific heat capacity of the body tissue (3.49 J·g^-1°C^–1) and ΔT_rec and ΔT_sk represent changes in T_rec and mean T_sk from immediately prior to the immersion period.

Fully instrumented nude body mass was recorded 5 min prior to the passive heating phase, upon towel drying following passive heat exposure and following the 60-min recovery phase. Changes in body mass in response to hot water immersion and to recovery were used to estimate whole body sweat loss, correcting for fluid consumption and urine output.

Thermal sensation

Thermal sensation was subjectively rated every 10 min throughout the recovery phase. The thermal sensation scale comprised of categories ranging from 0 (“unbearably cold”) to 8 (“unbearably hot”) in 0.5 increments [24].

Statistical analysis

All data were analysed using the Statistical Package for Social Sciences (version 27; SPSS Chicago, IL). Data are expressed as mean ± SD unless otherwise stated. Normality and sphericity were checked using the Shapiro-Wilk test and Mauchly’s test, respectively. A one-way repeated measures analysis of variance (ANOVA) was used to assess urine osmolality and baseline thermoregulatory measures between conditions. Analysis of T_rec, mean T_sk, heat storage, and thermal sensation during the recovery phase was performed using a 2 x 2 x 7 (SS condition x drink x time) repeated measures ANOVA. When a significant interaction effect was observed, and for data analysis between trials at one time point, one-way repeated measures ANOVAs were performed, P values of this post-hoc analyses were not adjusted for multiple comparisons [25]. Where assumptions of sphericity were violated, a Greenhouse-Geisser correction was applied. Significance was accepted at p ≤ 0.05 with trends defined as p = 0.05–0.10. When referring to multiple outcomes, the less-than operator (<) is used. For pairwise comparisons between conditions, effect sizes were expressed using Cohen d, with the magnitude of effect size classed as small (0.20), moderate (0.50) and large (0.80) [26].

Results

Resting measurements

Urine osmolality and resting body mass, T_rec, mean T_sk, room temperature and relative humidity did not differ between trials (Table 1). Due to personal discomfort, three participants were unable to complete their prescribed ingestion volume of ice slurry drink during ICE (n = 2, ingested volume 95% of target) and ICE-SS (n = 3, ingested volume 92% of target), however, drink volume was kept identical in subsequent trials and thus drink volume did not differ between trials. All participants arrived in a hydrated state (urine osmolality <700 mOsm [27]).

[Figure omitted. See PDF.]

Recovery phase

Thermoregulatory measures, heat storage and thermal sensation.

At the start of the recovery phase, T_rec, mean T_sk and thermal sensation did not differ between conditions (p = 0.935, 0.567 and 0.153, respectively).

During the 60-min recovery, there was a significant SS-condition x time and drink x time interaction for heat storage (p < 0.001). Post-hoc analysis revealed heat storage was lower from 10 min onwards in ICE and CON compared with ICE-SS and CON-SS (p ≤ 0.047, d ≥ 0.80; Fig 1A). However, the ice-slurry induced reduction in heat storage was delayed in the SS trials: whilst heat storage was lower for ICE compared with CON at 20 to 40 min (p ≤ 0.044, d ≥ 0.88), heat storage was lower for ICE-SS compared with CON-SS at 40 to 60 min (p ≤ 0.012, d ≥ 0.93).

[Figure omitted. See PDF.]

Heat storage (A), rectal temperature (T_rec; B), skin temperature (T_sk: C) and thermal sensation (D) in the recovery phase from hyperthermia. ICE (ice slurry, no sweat suit), CON (control drink, no sweat suit), ICE-SS (ice slurry, with sweat suit), CON-SS (control drink, with sweat suit). Significant interactions: ^†SS-condition x time, ^※drink x time; significant differences at individual time points: ^aICE vs CON, ^bICE-SS vs CON-SS, ^cCON vs CON-SS, ^dICE vs ICE-SS (p < 0.05), ^eCON vs ICE-SS. *Large and ^#moderate effect size, ICE vs CON; ^$large and ^¥moderate effect size, ICE-SS vs CON-SS; ^&large and ^§moderate effect size, ICE-SS vs CON.

There was a significant main effect of time (p < 0.001) and a drink x time interaction (p = 0.020) for T_rec. Post-hoc analysis revealed that T_rec was lower in ICE compared with CON from 30 to 60 min (p ≤ 0.034, d ≥ 0.53; Fig 1B), with the reduction in T_rec in ICE-SS compared with CON-SS approaching significance with a moderate effect size at 40 min (p = 0.079, d = 0.61). Further moderate and large effects sizes showed ice slurry induced reductions for both ICE vs CON (d = 0.53–0.80) and ICE-SS vs CON-SS (d = 0.53–0.61) (Fig 1).

There was a significant SS-condition x time interaction for both mean T_sk (p < 0.001, Fig 1C), mean T_sk was lower in ICE and CON compared with ICE-SS and CON-SS from 10 min onwards (p < 0.001). A reduction in mean T_sk for ICE compared with CON approached significance at 20 to 40 min with moderate effect sizes (p ≤ 0.099, d ≥ 0.53); mean T_sk did not differ between ICE-SS and CON-SS throughout the recovery phase (p ≥ 0.554, d ≤ 0.43).

There was a main effect for time, and interaction effects (SS-condition x time and drink x time) for thermal sensation (p = 0.001, p = 0.032 and p = 0.018; Fig 1D). Thermal sensation was greater in CON-SS than CON (p = 0.006, d = 0.57), but did not differ between ICE-SS and ICE (p = 0.130, d = 0.24). Whole body sweat loss during immersion and recovery did not differ between conditions (Table 2).

[Figure omitted. See PDF.]

Discussion

The aim of this study was to assess the cooling effectiveness of ice slurry ingestion in a state of compromised heat loss after passive heat exposure. This is the first study to explore the recovery from hyperthermia during heat loss restriction using ice slurry ingestion. Our research found that ice slurry ingestion resulted in a significant reduction in heat storage and T_rec when compared to ingesting a thermoneutral control drink, observed in both SS and no-SS trials. Despite overall comparable reductions in heat storage for SS and no-SS trials, we identified a delayed reduction in heat storage in SS trials. Additionally, a reduction in T_sk was only observed in no-SS trials following ice slurry ingestion. These data suggest that ice slurry ingestion can enhance recovery from hyperthermia and furthermore may be an effective cooling strategy for those experiencing hyperthermia due to compromised heat loss.

The greater T_sk during SS trials suggests the creation of a hot micro-environment that limited heat loss, which contributed to the greater heat storage in the SS trials compared with the no-SS trials. Analysis of heat storage is of particular interest, as it is suggested to be more reflective of overall tissue temperature changes within the body compared with T_rec alone [28], hence representing a holistic measure of thermal strain. The overall reduction in heat storage for both SS and no-SS indicates that ice slurry ingestion in the recovery from hyperthermia can reduce thermal strain regardless of the impact of compromised heat loss. This is in line with the ice-slurry induced reduction in T_core during exercise whilst wearing firefighter PPE [21] or raincoats [20], inducing a moderate rise in core temperature (~0.8–1.5°C). Interestingly, whilst Alhadad et al. (2021) found an ice-slurry induced reduction in gastrointestinal temperature during low intensity exercise, they did not observe this during moderate intensity exercise, inducing a higher rise in core temperature (~2°C). The authors suggest this to be likely due to the increased metabolic heat production and concluded ice slurry ingestion not to be effective in such conditions [20]. Whilst the present study investigated a similar 2°C rise in core temperature, the temperature rise investigated did not result from metabolic heat production but passive exposure to heat, which may explain why ice slurry proved to be effective in recovery from hyperthermia in the present study, but not during exercise investigated previously [20].

The timing of the greatest ice slurry induced reduction of heat storage differed between SS and no-SS trials, the biggest difference found earlier for no-SS trials. It is likely that the rise in heat storage during the early phases of recovery contributed this response. In contrast to ICE, during ICE-SS, heat storage did hence not return to baseline levels at 60 min. Prolonged ingestion time and/or larger quantities of slurry in conditions of considerable thermal strain may therefore be required to more effectively reduce heat storage [29]. This would be of particular interest for occupations where heat loss is limited by clothing microenvironments such as military personnel, firefighters and motorsport athletes, and in populations with impaired sweating ability such as those with spinal cord injury [2, 30].

The ice slurry ingestion induced reduction in T_rec aligns with previous research investigating ice slurry ingestion during passive recovery [10, 16, 29]. However, as the literature is ambiguous, the present results contrasts others. For example, Iwata et al. exposed participants to a hot (~38°C, ~40% RH, in which sweating is likely effective) and found no differences in T_rec and a trend for lower sweat rate in response to ice slurry ingestion [17]. This finding led to the suggestion that ice slurry ingestion may reduce sweating—and thus the evaporative heat loss potential from the skin—by an amount that is at least equivalent to the additional internal heat loss from ice slurry ingestion [31]. The findings of the present study do not support this theory for three reasons. First, when participants were exposed to dry, ambient conditions in which evaporative heat loss was likely effective (no-SS trials), ice slurry ingestion in fact did reduce T_rec. Second, if in line with that theory, our results should show an even more pronounced ice-slurry induced reduction in T_rec when heat loss was compromised in SS trials. However, this was not the case–whilst the moderate and large effect sizes imply that ice slurry ingestion also has the potential to reduce T_rec in SS trials, the ice-slurry induced difference in T_rec was not significant in SS trials but was significant in no-SS trials, likely explained by the evaporative heat loss from the skin in the no-SS condition. Third, no changes in sweat loss were found between conditions, suggesting that ice slurry ingestion per se did not impede evaporative cooling potential at the skin. Here we must point out that our findings are in contrast to previous studies that have reported lower sweat rates following ice slurry ingestion [15, 18], attributed to internal thermoreceptor activation, and hence potential for reduced evaporative heat loss [15]. In summary, the present results do not support the suggestion that ice slurry ingestion negatively affects heat dissipation at the skin [31]. In the present study, internal ice-slurry induced heat loss is likely the main mechanism to explain the moderate to large effect sizes for the reductions in heat storage and T_rec for the SS trials during recovery in ambient conditions. Contrasting findings within the literature regarding cooling capacity of ice slurries can be explained with differences in ambient conditions (facilitating evaporation or not), the cooling potential of the slurry (amount given, temperature), as well as differences in the experimental setup (timing, measurement procedures).

Ice slurry ingestion induced reductions in mean T_sk have been reported previously [10], even though T_sk has also been shown to be unaffected by ice slurry ingestion [31, 32]. In the present study, moderate effect sizes document a reduction in mean T_sk following ingestion of ice slurry in no-SS, which likely is the result of conduction, i.e., the blood surrounding the gastrointestinal area cooled by the ice slurry flowing to and cooling the skin. On the other hand, the lack of change in T_sk in SS trials is likely explained by the hot and humid microenvironment created by the SS, limiting convection and sweat evaporation to contribute to heat balance, likely counteracting any slurry-induced cooling of the skin. Whilst most skin surface heat loss in hot environments occurs via evaporation, with any modification to sweating and the evaporation of sweat having the greatest influence on heat balance [31], the reduction in T_sk therefore implies that conductive heat loss is a mechanism by which ice slurry ingestion exerts cooling.

The higher mean T_sk in the SS trials further explain the observed increases in thermal sensation, a mechanistic link that is established for T_sk [33]. Higher thermal sensation under conditions of compromised heat loss is also in line with previous research suggesting that individuals with impaired sweating ability (notably athletes with spinal cord injury) exhibit greater T_sk and increased thermal sensation than those without impaired sweating ability [34]. Interestingly, no thermal sensation differences were observed between SS and no-SS trials when ice slurries were ingested, indicating that ice slurry ingestion mitigates the increased thermal sensation associated with compromised heat loss. In addition, the present results highlight the effectiveness of ice slurry ingestion in reducing thermal sensation in both SS and no-SS trials and hence benefit conditions of normal as well as compromised heat loss.

We must note that a potential limitation of the present approach to determine heat storage lies in its calculation based on a two-compartment model, using measures of T_rec and T_sk alone. Indeed, more accurate estimations of heat storage during exercise include a contribution of the muscle compartment [28]. However, the present study investigated the recovery following passive heating in a non-exercising state which does not increase muscle temperature due to muscular work. Nonetheless, the inclusion of the muscle compartment, or calorimetry-based approaches for heat storage estimations, may be considered for any follow-up studies.

Conclusions

This study demonstrates that internal cooling using ice slurries can effectively reduce thermal strain following hyperthermia. Regardless of whether heat loss was compromised or not, ice slurry ingestion led to a decrease in heat storage. However, a delayed pattern for reducing markers of thermal strain was apparent in a state of compromised heat loss, which may be related to ice slurry ingestion not lowering T_sk in this state. The reduced heat storage was accompanied by a reduced T_rec, highlighted by moderate to large effect sizes in both SS and no-SS trials. Our findings suggest ice slurry ingestion can enhance recovery from hyperthermia, and furthermore may be an effective cooling strategy for individuals wearing clothing that inhibits convection and evaporation and populations with compromised sweating ability.

Supporting information

S1 Data. Rectal and skin temperature, heat storage, thermal sensation and all resting measures used in this study.

https://doi.org/10.1371/journal.pone.0305068.s001

(XLSX)

Acknowledgments

The authors would like to thank Sophie Goves, Chris Green, Boyu Duan, Jess Flint, Joe Craggs and Joseph Riley for assistance during data collection.

References

1. 1. Tatterson AJ, Hahn AG, Martini DT, Febbraio MA. Effects of heat stress on physiological responses and exercise performance in elite cyclists. J Sci Med Sport. 2000;3: 186–193. pmid:11104310

* View Article

* PubMed/NCBI

* Google Scholar

2. 2. House JR, Tipton MJ. Heat strain is reduced at different rates with hand, foot, forearm or lower leg cooling. Elsevier Ergon B Ser. 2005;3: 91–95.

* View Article

* Google Scholar

3. 3. Reilly T, Waterhouse J. Circadian aspects of body temperature regulation in exercise. Journal of Thermal Biology. 2009. pp. 161–170.

* View Article

* Google Scholar

4. 4. Freund PR, Brengelmann GL, Rowell LB, Halar E. Attenuated skin blood flow response to hyperthermia in paraplegic men. J Appl Physiol Respir Environ Exerc Physiol. 1984;56: 1104–1109. pmid:6725058

* View Article

* PubMed/NCBI

* Google Scholar

5. 5. Hopman MTE. Circulatory responses during arm exercise in individuals with paraplegia. Int J Sports Med. 1994;15: 126–131. pmid:8005724

* View Article

* PubMed/NCBI

* Google Scholar

6. 6. Guttmann L, Silver J, Wyndham CH. Thermoregulation in spinal man. J Physiol. 1958;142: 406–419. pmid:13576444

* View Article

* PubMed/NCBI

* Google Scholar

7. 7. Nybo L, Rasmussen P, Sawka MN. Performance in the heat-physiological factors of importance for hyperthermia-induced fatigue. Compr Physiol. 2014;4: 657–689. pmid:24715563

* View Article

* PubMed/NCBI

* Google Scholar

8. 8. Schmit C, Hausswirth C, Le Meur Y, Duffield R. Cognitive Functioning and Heat Strain: Performance Responses and Protective Strategies. Sport Med. 2017;47: 1289–1302. pmid:27988874

* View Article

* PubMed/NCBI

* Google Scholar

9. 9. Hocking C, Silberstein RB, Lau WM, Stough C, Roberts W. Evaluation of cognitive performance in the heat by functional brain imaging and psychometric testing. Comp Biochem Physiol Part A Mol Integr Physiol. 2001;128: 719–734. pmid:11282316

* View Article

* PubMed/NCBI

* Google Scholar

10. 10. Nakamura M, Nakamura D, Yasumatsu M, Takahashi H. Effect of ice slurry ingestion on core temperature and blood pressure response after exercise in a hot environment. J Therm Biol. 2021;98: 102922. pmid:34016346

* View Article

* PubMed/NCBI

* Google Scholar

11. 11. Bongers CCWG, Thijssen DHJ, Veltmeijer MTW, Hopman MTE, Eijsvogels TMH. Precooling and percooling (cooling during exercise) both improve performance in the heat: a meta-analytical review. Br J Sports Med. 2015;49: 377–384. pmid:24747298

* View Article

* PubMed/NCBI

* Google Scholar

12. 12. Bishop D. Warm up I: Potential mechanisms and the effects of passive warm up on exercise performance. Sport Med. 2003;33: 439–454. pmid:12744717

* View Article

* PubMed/NCBI

* Google Scholar

13. 13. Siegel R, Maté J, Brearley MB, Watson G, Nosaka K, Laursen PB. Ice slurry ingestion increases core temperature capacity and running time in the heat. Med Sci Sports Exerc. 2010;42: 717–725. pmid:19952832

* View Article

* PubMed/NCBI

* Google Scholar

14. 14. Ross MLR, Garvican LA, Jeacocke NA, Laursen PB, Abbiss CR, Martin DT, et al. Novel precooling strategy enhances time trial cycling in the heat. Med Sci Sports Exerc. 2011;43: 123–133. pmid:20508537

* View Article

* PubMed/NCBI

* Google Scholar

15. 15. Morris NB, Coombs G, Jay O. Ice slurry ingestion leads to a lower net heat loss during exercise in the heat. Med Sci Sports Exerc. 2016;48: 114–122. pmid:26258857

* View Article

* PubMed/NCBI

* Google Scholar

16. 16. Naito T, Haramura M, Muraishi K, Yamazaki M, Takahashi H. Impact of Ice Slurry Ingestion During Break-Times on Repeated-Sprint Exercise in the Heat. Sport Med Int Open. 2020;4: E45–E52. pmid:32395608

* View Article

* PubMed/NCBI

* Google Scholar

17. 17. Iwata R, Kawamura T, Hosokawa Y, Chang L, Suzuki K. Comparison of the effect of post-exercise cooling with ice slurry ingestion between males and females. J Therm Biol. 2021;99: 102979. pmid:34420623

* View Article

* PubMed/NCBI

* Google Scholar

18. 18. Siegel R, Maté J, Watson G, Nosaka K, Laursen PB. Pre-cooling with ice slurry ingestion leads to similar run times to exhaustion in the heat as cold water immersion. J Sports Sci. 2012;30: 155–165. pmid:22132792

* View Article

* PubMed/NCBI

* Google Scholar

19. 19. Gibson OR, James CA, Mee JA, Willmott AGB, Turner G, Hayes M, et al. Heat alleviation strategies for athletic performance: A review and practitioner guidelines. Temperature. 2020;7: 3–36. pmid:32166103

* View Article

* PubMed/NCBI

* Google Scholar

20. 20. Alhadad SB, Low ICC, Lee JKW. Thermoregulatory responses to ice slurry ingestion during low and moderate intensity exercises with restrictive heat loss. J Sci Med Sport. 2021;24: 105–109. pmid:32711957

* View Article

* PubMed/NCBI

* Google Scholar

21. 21. Ng J, Wingo JE, Bishop PA, Casey JC, Aldrich EK. Ice slurry ingestion and physiological strain during exercise in non-compensable heat stress. Aerosp Med Hum Perform. 2018;89: 434–441. pmid:29673428

* View Article

* PubMed/NCBI

* Google Scholar

22. 22. Ramanathan NL. A new weighting system for mean surface temperature of the human body. J Appl Physiol. 1964;19: 531–3. pmid:14173555

* View Article

* PubMed/NCBI

* Google Scholar

23. 23. Havenith G, Luttikholt VGM, Vrijkotte TGM. The relative influence of body characteristics on humid heat stress response. Eur J Appl Physiol Occup Physiol. 1995;70: 270–279. pmid:7607204

* View Article

* PubMed/NCBI

* Google Scholar

24. 24. Toner MM, Drolet LL, Pandolf KB. Perceptual and Physiological Responses during Exercise in Cool and Cold Water. Percept Mot Skills. 1986;62: 211–220. pmid:3960662

* View Article

* PubMed/NCBI

* Google Scholar

25. 25. Perneger T V. What’s wrong with Bonferroni adjustments. BMJ. 1998;316: 1236 LP– 1238. pmid:9553006

* View Article

* PubMed/NCBI

* Google Scholar

26. 26. Cohen J. Statistical power analysis for the behavioral sciences. Second Edi. Hillsdale, New Jersey: Lawrence Erlbaum Associates; 1988. https://doi.org/10.1007/BF00544941

27. 27. Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. Exercise and fluid replacement. Med Sci Sports Exerc. 2007;39: 377–390. pmid:17277604

* View Article

* PubMed/NCBI

* Google Scholar

28. 28. Jay O, Gariépy LM, Reardon FD, Webb P, Ducharme MB, Ramsay T, et al. A three-compartment thermometry model for the improved estimation of changes in body heat content. Am J Physiol—Regul Integr Comp Physiol. 2007;292: R167–R175. pmid:16931653

* View Article

* PubMed/NCBI

* Google Scholar

29. 29. Stanley J, Leveritt M, Peake JM. Thermoregulatory responses to ice-slush beverage ingestion and exercise in the heat. Eur J Appl Physiol. 2010;110: 1163–1173. pmid:20714767

* View Article

* PubMed/NCBI

* Google Scholar

30. 30. Forsyth P, Pumpa K, Knight E, Miller J. Physiological and perceptual effects of precooling in wheelchair basketball athletes. J Spinal Cord Med. 2016;39: 671–678. pmid:27192132

* View Article

* PubMed/NCBI

* Google Scholar

31. 31. Jay O, Morris NB. Does Cold Water or Ice Slurry Ingestion During Exercise Elicit a Net Body Cooling Effect in the Heat? Sport Med. 2018;48: 17–29. pmid:29368184

* View Article

* PubMed/NCBI

* Google Scholar

32. 32. Ihsan M, Landers G, Brearley M, Peeling P. Beneficial Effects of Ice Ingestion as a Precooling Strategy on 40-km Cycling Time-Trial Performance. Int J Sports Physiol Perform. 2010;5: 140–151. pmid:20625187

* View Article

* PubMed/NCBI

* Google Scholar

33. 33. Schlader ZJ, Simmons SE, Stannard SR, Mündel T. Skin temperature as a thermal controller of exercise intensity. Eur J Appl Physiol. 2011;111: 1631–1639. pmid:21197543

* View Article

* PubMed/NCBI

* Google Scholar

34. 34. Griggs KE, Havenith G, Price M, Mason BS, Goosey-Tolfrey VL. Thermoregulatory Responses during Competitive Wheelchair Rugby Match Play. Int J Sports Med. 2017;38: 177–183. pmid:28192830

* View Article

* PubMed/NCBI

* Google Scholar

Citation: O’Brien TJ, Goosey-Tolfrey VL, Leicht CA (2024) Compromised heat loss leads to a delayed ice slurry induced reduction in heat storage. PLoS ONE 19(8): e0305068. https://doi.org/10.1371/journal.pone.0305068

About the Authors:

Thomas J. O’Brien

Roles: Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

E-mail: [email protected] (TJO); [email protected] (CAL)

Affiliation: Peter Harrison Centre for Disability Sport; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom

ORICD: https://orcid.org/0000-0002-0523-2826

Victoria L. Goosey-Tolfrey

Roles: Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation: Peter Harrison Centre for Disability Sport; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom

Christof A. Leicht

Roles: Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

E-mail: [email protected] (TJO); [email protected] (CAL)

Affiliation: Peter Harrison Centre for Disability Sport; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom

ORICD: https://orcid.org/0000-0002-3539-8480

[/RAW_REF_TEXT]

References

1. Tatterson AJ, Hahn AG, Martini DT, Febbraio MA. Effects of heat stress on physiological responses and exercise performance in elite cyclists. J Sci Med Sport. 2000;3: 186–193. pmid:11104310

2. House JR, Tipton MJ. Heat strain is reduced at different rates with hand, foot, forearm or lower leg cooling. Elsevier Ergon B Ser. 2005;3: 91–95.

3. Reilly T, Waterhouse J. Circadian aspects of body temperature regulation in exercise. Journal of Thermal Biology. 2009. pp. 161–170.

4. Freund PR, Brengelmann GL, Rowell LB, Halar E. Attenuated skin blood flow response to hyperthermia in paraplegic men. J Appl Physiol Respir Environ Exerc Physiol. 1984;56: 1104–1109. pmid:6725058

5. Hopman MTE. Circulatory responses during arm exercise in individuals with paraplegia. Int J Sports Med. 1994;15: 126–131. pmid:8005724

6. Guttmann L, Silver J, Wyndham CH. Thermoregulation in spinal man. J Physiol. 1958;142: 406–419. pmid:13576444

7. Nybo L, Rasmussen P, Sawka MN. Performance in the heat-physiological factors of importance for hyperthermia-induced fatigue. Compr Physiol. 2014;4: 657–689. pmid:24715563

8. Schmit C, Hausswirth C, Le Meur Y, Duffield R. Cognitive Functioning and Heat Strain: Performance Responses and Protective Strategies. Sport Med. 2017;47: 1289–1302. pmid:27988874

9. Hocking C, Silberstein RB, Lau WM, Stough C, Roberts W. Evaluation of cognitive performance in the heat by functional brain imaging and psychometric testing. Comp Biochem Physiol Part A Mol Integr Physiol. 2001;128: 719–734. pmid:11282316

10. Nakamura M, Nakamura D, Yasumatsu M, Takahashi H. Effect of ice slurry ingestion on core temperature and blood pressure response after exercise in a hot environment. J Therm Biol. 2021;98: 102922. pmid:34016346

11. Bongers CCWG, Thijssen DHJ, Veltmeijer MTW, Hopman MTE, Eijsvogels TMH. Precooling and percooling (cooling during exercise) both improve performance in the heat: a meta-analytical review. Br J Sports Med. 2015;49: 377–384. pmid:24747298

12. Bishop D. Warm up I: Potential mechanisms and the effects of passive warm up on exercise performance. Sport Med. 2003;33: 439–454. pmid:12744717

13. Siegel R, Maté J, Brearley MB, Watson G, Nosaka K, Laursen PB. Ice slurry ingestion increases core temperature capacity and running time in the heat. Med Sci Sports Exerc. 2010;42: 717–725. pmid:19952832

14. Ross MLR, Garvican LA, Jeacocke NA, Laursen PB, Abbiss CR, Martin DT, et al. Novel precooling strategy enhances time trial cycling in the heat. Med Sci Sports Exerc. 2011;43: 123–133. pmid:20508537

15. Morris NB, Coombs G, Jay O. Ice slurry ingestion leads to a lower net heat loss during exercise in the heat. Med Sci Sports Exerc. 2016;48: 114–122. pmid:26258857

16. Naito T, Haramura M, Muraishi K, Yamazaki M, Takahashi H. Impact of Ice Slurry Ingestion During Break-Times on Repeated-Sprint Exercise in the Heat. Sport Med Int Open. 2020;4: E45–E52. pmid:32395608

17. Iwata R, Kawamura T, Hosokawa Y, Chang L, Suzuki K. Comparison of the effect of post-exercise cooling with ice slurry ingestion between males and females. J Therm Biol. 2021;99: 102979. pmid:34420623

18. Siegel R, Maté J, Watson G, Nosaka K, Laursen PB. Pre-cooling with ice slurry ingestion leads to similar run times to exhaustion in the heat as cold water immersion. J Sports Sci. 2012;30: 155–165. pmid:22132792

19. Gibson OR, James CA, Mee JA, Willmott AGB, Turner G, Hayes M, et al. Heat alleviation strategies for athletic performance: A review and practitioner guidelines. Temperature. 2020;7: 3–36. pmid:32166103

20. Alhadad SB, Low ICC, Lee JKW. Thermoregulatory responses to ice slurry ingestion during low and moderate intensity exercises with restrictive heat loss. J Sci Med Sport. 2021;24: 105–109. pmid:32711957

21. Ng J, Wingo JE, Bishop PA, Casey JC, Aldrich EK. Ice slurry ingestion and physiological strain during exercise in non-compensable heat stress. Aerosp Med Hum Perform. 2018;89: 434–441. pmid:29673428

22. Ramanathan NL. A new weighting system for mean surface temperature of the human body. J Appl Physiol. 1964;19: 531–3. pmid:14173555

23. Havenith G, Luttikholt VGM, Vrijkotte TGM. The relative influence of body characteristics on humid heat stress response. Eur J Appl Physiol Occup Physiol. 1995;70: 270–279. pmid:7607204

24. Toner MM, Drolet LL, Pandolf KB. Perceptual and Physiological Responses during Exercise in Cool and Cold Water. Percept Mot Skills. 1986;62: 211–220. pmid:3960662

25. Perneger T V. What’s wrong with Bonferroni adjustments. BMJ. 1998;316: 1236 LP– 1238. pmid:9553006

26. Cohen J. Statistical power analysis for the behavioral sciences. Second Edi. Hillsdale, New Jersey: Lawrence Erlbaum Associates; 1988. https://doi.org/10.1007/BF00544941

27. Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. Exercise and fluid replacement. Med Sci Sports Exerc. 2007;39: 377–390. pmid:17277604

28. Jay O, Gariépy LM, Reardon FD, Webb P, Ducharme MB, Ramsay T, et al. A three-compartment thermometry model for the improved estimation of changes in body heat content. Am J Physiol—Regul Integr Comp Physiol. 2007;292: R167–R175. pmid:16931653

29. Stanley J, Leveritt M, Peake JM. Thermoregulatory responses to ice-slush beverage ingestion and exercise in the heat. Eur J Appl Physiol. 2010;110: 1163–1173. pmid:20714767

30. Forsyth P, Pumpa K, Knight E, Miller J. Physiological and perceptual effects of precooling in wheelchair basketball athletes. J Spinal Cord Med. 2016;39: 671–678. pmid:27192132

31. Jay O, Morris NB. Does Cold Water or Ice Slurry Ingestion During Exercise Elicit a Net Body Cooling Effect in the Heat? Sport Med. 2018;48: 17–29. pmid:29368184

32. Ihsan M, Landers G, Brearley M, Peeling P. Beneficial Effects of Ice Ingestion as a Precooling Strategy on 40-km Cycling Time-Trial Performance. Int J Sports Physiol Perform. 2010;5: 140–151. pmid:20625187

33. Schlader ZJ, Simmons SE, Stannard SR, Mündel T. Skin temperature as a thermal controller of exercise intensity. Eur J Appl Physiol. 2011;111: 1631–1639. pmid:21197543

34. Griggs KE, Havenith G, Price M, Mason BS, Goosey-Tolfrey VL. Thermoregulatory Responses during Competitive Wheelchair Rugby Match Play. Int J Sports Med. 2017;38: 177–183. pmid:28192830