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Abstract
The KATITA-25 (Kidney AlloTransplant Immunosuppressive Therapy Adherence) Questionnaire is a multidimensional self-administered scale developed in Brazilian Portuguese that measures the predisposition for non-adherence to immunosuppressive medication in candidate patients for kidney transplantation, in the pre-transplant setting. The aim of this study was the cross-cultural validation of the Spanish version of the KATITA-25 scale. The translation/back-translation method was used, followed by cognitive interviews and a pre-test. The Spanish version of KATITA-25 was administered to 163 candidate patients for kidney transplantation from 2 kidney transplant centres and 2 dialysis centres in Catalonia, Spain. The scale was re-administered to the first 79 patients included into the study, after a 2 to 4 weeks interval. Internal consistency was assessed using Cronbach’s alpha, test–retest reliability with the intraclass correlation coefficient (ICC); construct validity with goodness of fit indices after confirmatory factor analysis using structural equation modelling. The Cronbach’s alpha of the Spanish version was 0.83, the ICC was 0.86. Confirmatory factor analysis showed adequate fit of the structural model. Overall, the analytical results closely resembled those obtained in the validation of the original scale. In conclusion, this cross-cultural validation study showed adequate reliability and construct validity of the Spanish version of the KATITA-25 questionnaire.
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1 Universidade Federal do Rio Grande do Norte, Postgraduate Program in Pharmaceutical Science, Centro de Ciências da Saúde, Natal, Brazil (GRID:grid.411233.6) (ISNI:0000 0000 9687 399X); Universidade Federal do Rio Grande do Norte, Clinical Pharmacy Unit, Onofre Lopes University Hospital, Centro de Ciências da Saúde, Natal, Brazil (GRID:grid.411233.6) (ISNI:0000 0000 9687 399X)
2 Hospital del Mar, Nephrology Department, Barcelona, Spain (GRID:grid.411142.3) (ISNI:0000 0004 1767 8811)
3 Unitat de Diàlisi, Hospital Terrassa, Barcelona, Spain (GRID:grid.414584.8) (ISNI:0000 0004 1770 3095)
4 Hospital de Mollet, Unitat de Diàlisi, Barcelona, Spain (GRID:grid.414584.8)
5 Hospital Universitario de Bellvitge, Servicio de Trasplantament Renal, Barcelona, Spain (GRID:grid.411129.e) (ISNI:0000 0000 8836 0780)
6 Universitat Central de Catalunya, Centre for Health and Social Care Research (CESS), Universitat de Vic, Vic, Spain (GRID:grid.440820.a)
7 Universidade Federal do Rio Grande do Norte, Postgraduate Program in Pharmaceutical Science, Centro de Ciências da Saúde, Natal, Brazil (GRID:grid.411233.6) (ISNI:0000 0000 9687 399X); Universidade Federal do Rio Grande do Norte, Departamento de Farmácia, Centro de Ciências da Saúde, Natal, Brazil (GRID:grid.411233.6) (ISNI:0000 0000 9687 399X)
8 Universidade Federal do Rio Grande do Norte, Departamento de Farmácia, Centro de Ciências da Saúde, Natal, Brazil (GRID:grid.411233.6) (ISNI:0000 0000 9687 399X)




