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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Simple Summary

Gut microbiota significantly influences dogs’ well-being, and several researchers have made strides in characterizing canine gut microbiota composition. Recent research has revealed that the canine gut microbiota is highly impacted by the type of diet. Prebiotics (non-digestible oligosaccharides able to promote the growth of beneficial bacteria) and probiotics (live microorganisms that confer a health benefit by enhancing microbial diversity) can modulate the gut microbiota and promote gastrointestinal health. A growing interest has recently been in combining prebiotics and probiotics (synbiotics) to achieve synergistic effects. The present study aimed to investigate the effects of supplementation with a prebiotic (Microbiotal) and a probiotic (L. reuteri) using the fecal microbiota of a healthy canine donor. The investigators used a novel in vitro fermentation platform (SCIME™), which closely mimics the canine gastrointestinal tract, allowing long-term experiments. This study demonstrates the promising modulatory effects of prebiotics and probiotics, especially when combined.

Details

Title
Modulation of Canine Gut Microbiota by Prebiotic and Probiotic Supplements: A Long-Term In Vitro Study Using a Novel Colonic Fermentation Model
Author
Gramenzi, Alessandro 1 ; Clerico, Luana 2 ; Belà, Benedetta 1   VIAFID ORCID Logo  ; Meri Di Leonardo 3 ; Fusaro, Isa 1   VIAFID ORCID Logo  ; Pignataro, Giulia 1   VIAFID ORCID Logo 

 Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy; [email protected] (A.G.); [email protected] (B.B.); [email protected] (I.F.) 
 Independent Researcher, 17100 Savona, Italy; [email protected] 
 Azienda Sanitaria Locale di Teramo, 64100 Teramo, Italy; [email protected] 
First page
3342
Publication year
2024
Publication date
2024
Publisher
MDPI AG
e-ISSN
20762615
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3132827133
Copyright
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.