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Abstract
Lyme borreliosis (LB) is a multisystem infectious disease abundant in the northern countries of the world and is caused by Borrelia species. Vaccination against LB is an effective way to prevent and reduce the number of diseases in endemic areas. Several vaccines have been developed and tested in the past, but no human LB vaccine is currently available on the market. This review aims to uncover and delineate various strategies and diverse technological approaches related to vaccine production. Furthermore, we characterize already tested vaccines, possibilities for their future development, and reasons for their failure.
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Details
1 Faculty of Medicine, Pavol Jozef Safarik University in Košice, Rastislavova 43, 041 90 Košice
2 Centre of Experimental and Clinical Regenerative Medicine
3 Laboratory of biomedical microbiology and immunology, University of Veterinary Medicine and Pharmacy, Komenského 73, 041 81, Košice, Slovakia