Abstract

Introduction: Perforated appendicitis (PA) in children is associated with a considerable risk for postoperative complications (POCs) such as wound infection and intra-abdominal abscess.

The aim of this study was to determine the diagnostic accuracy of hematological parameters in the early POC detection in children after PA surgery.

Materials and Methods: The study enrolled 71 patients with PA divided into two groups: 14 patients with POC (POC+ group) and 57 patients without POC (POC− group). Clinical and hematological parameters were followed preoperatively, prior to the surgery (PRO) and postoperatively on day 2 (POD2) and day 4 (POD4).

Results: The POC+ group had longer duration of higher axillar temperature as well as extended intensive and inpatient care. This group also had a significantly lower absolute neutrophil count ratio between POD2 and POD4. According to the receiver operating characteristic curve analysis, relative neutrophil count on POD4 higher than 71.8% and the ratio of absolute neutrophil count between POD2 and POD4 lower than 44.5% were found to be useful for predicting POC.

Conclusion: Absolute neutrophil count ratio between POD2 and POD4 and relative neutrophil count at POD4 could be efficient in identifying children at higher risk of developing POC after PA surgery.

Details

Title
Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis
Author
Marjanovic, Vesna 1 ; Budic, Ivana 1 ; Jankovic-Velickovic, Ljubinka 2 ; Stevic, Marija 3 ; Kostic, Milos 4 ; Simic, Dusica 5 

 Department of Anesthesiology and Reanimatology, Faculty of Medicine, University of Nis, Serbia; Clinic for Anesthesia and Intensive Therapy, Clinical Centre Nis, Serbia 
 Department of Pathology, Faculty of Medicine, University of Nis, Serbia; Centre of Pathology, Clinical Centre Nis, Serbia 
 Department of Surgery with Anesthesiology, Faculty of Medicine, University of Belgrade, Serbia; Department of Anesthesiology, Reanimatology and Intensive Therapy, University Children’s Hospital, Belgrade, Serbia 
 Department of Immunology, Faculty of Medicine, University of Nis, Serbia 
 Department of Surgery with Anesthesiology, Faculty of Medicine, University of Belgrade, Serbia; Department of Anesthesiology, Reanimatology and Intensive Therapy, University Children’s Hospital, Serbia 
Pages
77-84
Publication year
2021
Publication date
2021
Publisher
De Gruyter Poland
ISSN
18416624
e-ISSN
22845623
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3158696043
Copyright
© 2021. This work is published under http://creativecommons.org/licenses/by-nc-nd/3.0 (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.